Fig. 6.

Association between muscle and plasma humanin levels and ERK phosphorylation and BAX mRNA expression in untrained. ERK (extracellular signal-regulated kinases) phosphorylation (A) and BAX mRNA (B) expression at rest (Pre) Pre and immediately (Post) and 4 h (4 h) following untrained acute high-intensity exercise before high-intensity interval training (HIIT). Correlations between humanin plasma and muscle levels and BAX mRNA expression (C, D) in response to acute high-intensity exercise before HIIT. Curved dotted lines represent 95% confidence intervals. *P < 0.01 vs. Pre for one-way ANOVA.