. 2020 Nov 5:zwaa080. doi: 10.1093/eurjpc/zwaa080

Table 1.

Results of the Delphi Questionnaire

	Round 1: Questionnaire development		Round 2			Round 3
n	Question		Mean	SD	Intermediate consensus	Mean	SD	Final consensus
n	Question		n	n	Intermediate consensus	n	n	Final consensus
Open question: which are appropriate referrals to CR in the COVID-19 era?
1	Primary diagnosis: CV disease	All patients with primary cardiovascular diagnosis of ‘post-ACS and post-primary PCI’ should be referred to CR, independently from the history of COVID-19	3.74	2.86	For	4.22	2.11	For (confirmed)
2		All patients with primary cardiovascular diagnosis of ‘chronic coronary syndromes’ should be referred to CR, independently from the history of COVID-19	2.77	3.05	NC	3.14	2.51	For (new)
3		All patients with primary cardiovascular diagnosis of ‘coronary artery or valve heart surgery’ should be referred to CR, independently from the history of COVID-19	3.41	2.95	For	3.91	2.27	For (confirmed)
4		All patients with primary cardiovascular diagnosis of ‘chronic heart failure’ should be referred to CR, independently from the history of COVID-19	3.35	2.85	For	3.96	2.14	For (confirmed)
5		All patients with primary cardiovascular diagnosis of ‘cardiac transplantation’ should be referred to CR, independently from the history of COVID-19	2.74	3.11	NC	3.09	2.59	For (new)
6		All patients with primary cardiovascular diagnosis of ‘device implantation’ should be referred to CR, independently from the history of COVID-19	2.14	3.43	NC	2.64	3.09	NC
7		All patients with primary cardiovascular diagnosis of ‘presence of ventricular assist device’ should be referred to CR, independently from the history of COVID-19	2.48	3.60	NC	3.13	2.96	For (new)
8		All patients with primary cardiovascular diagnosis of ‘peripheral artery disease’ should be referred to CR, independently from the history of COVID-19	2.04	3.15	NC	2.57	2.86	NC
9		Only patients with ischaemic heart disease as primary cardiovascular qualifying diagnosis to CR should be referred to CR, independently from the history of COVID-19	−2.26	3.60	NC	−2.26	3.60	NC
10		Patients with CHF should not be referred’ as referral of this group (i.e. the exercise programme) is more controversial due to the high risk of centre-based CR and safety concerns of telerehabilitation	−1.73	3.79	NC	−2.09	3.49	NC
11		Aged/frail patients should not be referred’ as referral of this group (i.e. the exercise programme) is more controversial due to the high risk of centre-based CR and safety concerns of telerehabilitation	−0.82	3.74	NC	−1.09	3.45	NC
12		Priorities on which primary cardiovascular qualifying diagnosis should be referred to CR, independently from the history of COVID-19, should be defined at a local level (Hospital/Institution/CR facility)	2.77	3.04	NC	2.95	2.85	For (new)
13		Only patients with a primary cardiovascular qualifying diagnosis to CR and a history of COVID-19 should be referred to CR	−2.04	4.19	NC	−2.39	3.90	NC
14		CV patients referred to CR should have no history of COVID-19	−2.39	3.07	NC	−2.74	2.61	Against (new)
15		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced invasive ventilation	−3.30	2.69	Against	−3.30	2.69	Against (confirmed)
16		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced non-invasive ventilation	−3.26	2.78	Against	−3.70	2.14	Against (confirmed)
17		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced stay in ICUs	−2.96	3.05	NC	−3.39	2.54	Against (new)
18		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced hypoxia	−3.35	2.69	Against	−3.78	2.00	Against (confirmed)
19		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced viral pneumonia	−3.70	2.12	Against	−3.70	2.12	Against (confirmed)
20		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those having experienced any kind of symptom	−3.00	2.91	Against	−3.00	2.91	Against (confirmed)
21		Patients referred with a primary qualifying diagnosis for CR and a history of COVID-19 are limited to those aged >75 and/or frail, whichever symptoms of COVID-19	−3.39	2.81	Against	−3.43	2.76	Against (confirmed)
22	Primary diagnosis: COVID-19	COVID-19 patients should be referred to CR, independently from the history of CV disease	−2.43	3.62	NC	−2.78	3.23	NC
23		COVID-19 patients with pre-existing cardiovascular disease should be referred to CR	1.17	3.73	NC	1.09	3.65	NC
24		COVID-19 patients with multiple CV risk factors should be referred to CR	1.64	3.51	NC	1.55	3.45	NC
25		COVID-19 patients complicated by one or more adverse cardiac symptoms/events (angina pectoris, ACS, exacerbation of heart failure, cardiogenic shock, myocarditis, arrhythmias, resuscitated SCD, pericarditis/cardiac tamponade, and/or arterial/venous thromboembolic events) should be referred to CR	3.68	2.68	For	3.68	2.68	For (confirmed)
26		COVID-19 patients requiring percutaneous coronary intervention and/or CIED implantation should be referred to CR	3.50	2.52	For	3.50	2.52	For (confirmed)
27		COVID-19 patients developing pulmonary arterial hypertension should be referred to CR	2.91	2.45	For	2.91	2.45	For (confirmed)
28		COVID-19 patients with prolonged stay in ICU should be referred to CR	0.95	4.04	NC	0.86	3.97	NC
29		COVID-19 patients developing markedly reduced exercise tolerance should be referred to CR	1.59	3.95	NC	1.50	3.89	NC
30		COVID-19 patients developing cardiovascular complications from therapeutic agents should be referred to CR	2.41	3.19	NC	2.32	3.14	NC
31		COVID-19 patients with coagulation alterations should be referred to CR	−0.09	4.13	NC	−0.27	3.98	NC
			Consensus rate: 39%			Consensus rate: 58%
Comments: Patients should not be active COVID-19 (regardless of criteria for referral, CR should take place only if a qualified and recent COVID-19 test is negative) In the referral process, a tailored ‘post-COVID’ rehabilitation programme with cardiological support should be always considered as an alternative When evaluating appropriate referral to CR for CV patients, it’s important to differentiate between post-acute and chronic conditions also (possibility of delayed referral in chronic CVD) As an alternative approach, referral could be delayed if physical activity and secondary prevention is sufficiently maintained The ‘healed’ COVID-19 infection has to be confirmed by the referring institution or referring doctor If recent COVID-19 infection, period of 5 weeks after symptom onset should be respected When considering CHF patients, priority to class III–IV could be considered Need of special considerations for HTX patients: (i) CR only in specialized CR institutions and in close interaction with the transplant heart centre; (ii) CR participation based on individual decisions, taking into consideration the local situation; (iii) the decision always has to take the local and individual risk into consideration The local implementation of adequate strategies for contagion risk reduction, the potential reduction in the number of CR programmes available and the possible reduction in the number of health care professionals dedicated to CR (because of COVID ward’s needs, at least in the first phase) might limit the number of patients that can be enrolled in CR. All these points should prompt the definition of local priorities, trying to enrol the largest possible number of patients COVID patients without CV disease seem more suitable for geriatric/pulmonary rehabilitation
Open question: which are the optimal timing and setting of CR in the COVID-19 era?
32	Patients without history of COVID	In patients without history of COVID there is no need to modify usual policies/recommendations for timing and setting	1.78	3.72	NC	2.30	3.28	NC
33		In patients without history of COVID there is need for fast track (time from referral to entry <15 days) by CR centres	1.78	3.23	NC	2.13	2.87	NC
34		In patients without history of COVID there is need for delayed track by CR centres	−1.70	3.55	NC	−2.26	3.25	NC
35		In patients without history of COVID the home environment should be preferred to limit people’s movements	1.70	2.57	NC	2.09	2.15	NC
36		In patients without history of COVID the outpatient setting should be preferred to avoid contacts with hospitalized patients and health operators	2.87	2.40	For	2.87	2.40	For (confirmed)
37	Patients with history of COVID	In COVID-19 patients CR (mainly exercise component) should begin during the acute phase of the viral disease if the patient is not haemodynamically unstable	−3.10	3.06	Against	−3.48	2.44	Against (confirmed)
38		In COVID-19 patients CR should begin after clinical recovery of pneumonia	1.00	3.86	NC	1.33	3.61	NC
39		In COVID-19 patients CR should begin after radiologic recovery of pneumonia	−0.14	3.80	NC	−0.38	3.53	NC
40		In COVID-19 patients CR should begin after resolution of COVID-19 induced hypoxia	2.14	3.34	NC	2.29	3.42	NC
41		In COVID-19 patients CR should begin when no more clinical signs	0.38	4.17	NC	0.95	3.77	NC
42		In COVID-19 patients CR should begin after the end of COVID-19 treatment regimen	−0.33	3.75	NC	−0.24	3.65	NC
43		In COVID-19 patients CR should begin after NIV has been stopped	0.00	4.10	NC	0.33	3.80	NC
44		In COVID-19 patients CR should begin when the P/f value is above 100	−1.50	2.50	NC	−1.41	2.45	NC
45		In COVID-19 patients CR should begin when the P/f value is above 200	0.00	2.48	NC	0.47	2.12	NC
46		In COVID-19 patients CR should begin when the P/f value is above 300	1.31	2.50	NC	1.24	2.44	NC
47		In COVID-19 patients the beginning of CR is independent from arterial blood gas parameters	−1.71	3.36	NC	−1.95	3.02	NC
48		In COVID-19 patients CR should begin after two negative nasopharyngeal specimens for COVID-19	1.43	3.80	NC	1.52	3.66	NC
49		In COVID-19 patients CR should always comprise a first residential step	−0.68	3.17	NC	−0.68	3.17	NC
50		In COVID-19 patients CR should always comprise an outpatient step	0.64	3.35	NC	0.64	3.35	NC
51		In COVID-19 patients CR should be always offered as home-rehabilitation or mixed programmes when appropriate (if available)	2.33	3.14	NC	2.43	3.19	NC
52		In COVID-19 patients enrolled in ambulatory or home-rehabilitation programmes, digital health tools should be integrated by tracing systems (Gps)	2.18	3.08	NC	2.18	3.08	NC
			Consensus rate: 10%			Consensus rate: 10%
Comments: When considering timing and setting, the clinical severity, local situation (social barriers), and functional limitation need to be strictly considered Special attention to false negative nasopharyngeal specimens for COVID-19 The home environment is dependent on the local COVID-19 situation and national recommendations/laws The ‘acute phase’ of COVID-19 has many different clinical manifestations. Patients may be unable to perform physical exercise not because of haemodynamic instability, but because of severe respiratory and/or neuromuscular impairment Phase I CR could be considered with specific intervention by trained physiotherapist: (i) ventilation support/weaning with monitoring of clinical conditions (parameters and signs) and adjustment of oxygen therapy; (ii) disability prevention with mobilization (getting patient out of bed if there is clinical stability), frequent posture changes/continuous rotational therapy, therapeutic postures (early sitting/pronation), and mild active limb exercises; (iii) chest physiotherapy. Non-productive dry cough should be sedated to avoid fatigue and dyspnoea and bronchial clearance techniques should be carry out for hypersecretive patients with chronic respiratory diseases, by preferably using disposable devices with self-management.
Open question: which are the core components of CR in the COVID-19 era?
53	Patients without history of COVID	In patients without history of COVID there is no need to modify usual policies/recommendations for core components delivery	1.87	4.30	NC	2.17	4.01	NC
54		In patients without history of COVID there is need to exclude the presence of COVID-19	2.61	2.87	NC	2.65	2.42	For (new)
55		In patients without history of COVID there is need to modify the core component ‘patient assessment’	−0.87	4.04	NC	−0.78	3.97	NC
56		In patients without history of COVID there is need to modify the core component ‘physical activity counselling’	−0.95	3.80	NC	−0.86	3.72	NC
57		In patients without history of COVID there is need to modify the core component ‘exercise training’	−1.09	4.01	NC	−1.18	3.89	NC
58		In patients without history of COVID there is need to modify the core component ‘diet/nutritional counselling’	−2.91	2.96	NC	−2.82	2.92	NC
59		In patients without history of COVID there is need to modify the core component ‘weight control management’	−2.82	2.95	NC	−2.82	2.95	NC
60		In patients without history of COVID there is need to modify the core component ‘lipid management’	−2.77	2.96	NC	−2.77	2.96	NC
61		In patients without history of COVID there is need to modify the core component ‘blood pressure management’	−2.82	2.97	NC	−2.82	2.97	NC
62		In patients without history of COVID there is need to modify the core component ‘smoking cessation’	−2.91	2.83	Against	−2.91	2.83	Against (confirmed)
63		In patients without history of COVID there is need to modify the core component ‘psychosocial management’	−1.09	4.10	NC	−1.00	4.03	NC
64		In patients without history of COVID there is need to include specific education on COVID-19	3.00	2.91	For	3.43	2.35	For (confirmed)
65	Patients with history of COVID	In patients with history of COVID-19 usual core components of CR delivery should be supplemented with other specific interventions	3.09	3.10	NC	3.45	2.52	For (new)
66		Core component ‘patient evaluation’. Patient evaluation should always comprise respiratory impairment and other COVID-19 features	3.57	2.50	For	3.57	2.50	For (confirmed)
67		Core component ‘patient evaluation’. Chest X-ray should always be performed at beginning of the CR programme	1.43	3.63	NC	1.90	3.30	NC
68		Core component ‘patient evaluation’. Nasopharyngeal specimen should always be performed at beginning of the CR programme	1.05	3.97	NC	1.75	3.58	NC
69		Core component ‘patient evaluation’. Nasopharyngeal specimen should always be performed during of the CR programme	−0.80	3.65	NC	−0.10	3.63	NC
70		Core component ‘patient evaluation’. Serology for COVID-19 should always be performed at beginning of the CR programme	−0.20	3.78	NC	0.45	3.61	NC
71		Core component ‘patient evaluation’. Serology for COVID-19 should always be performed during the CR programme	−2.45	3.43	NC	−2.20	3.41	NC
72		Core component ‘patient evaluation’. Chest CT-scan should always be performed during the CR programme	−1.85	3.38	NC	−1.75	3.31	NC
73		Core component ‘patient evaluation’. Arterial blood gas analysis should always be performed during the CR programme	−0.10	3.78	NC	−0.19	3.72	NC
74		Core component ‘patient evaluation’. Direct testing of exercise capacity (CPET preferred) should always be performed at the start of the CR programme	3.14	2.46	For	3.14	2.46	For (confirmed)
75		Core component ‘patient evaluation’. Indirect testing for exercise capacity should always be performed at the start of the CR programme	2.38	2.96	NC	2.38	2.96	NC
76		Core component ‘patient evaluation’. Frailty should always be investigated during the CR programme	3.05	2.80	For	3.05	2.80	For (confirmed)
77		Core component ‘patient evaluation’. History of COVID-19 (symptomatic or asymptomatic) among family and caregivers should always be collected	2.90	3.05	NC	3.00	2.98	For (new)
78		In patients with history of COVID there is need to modify the core component ‘physical activity counselling’	1.10	4.18	NC	1.48	3.96	NC
79		Core component ‘exercise training’. IMT and/or other respiratory techniques should be included as normally indicated in the exercise training programme	2.76	3.02	NC	2.76	2.58	For (new)
80		Core component ‘exercise training’. Strength training in COVID-19 should be included as normally indicated in CR programmes	3.71	1.98	For	3.67	1.96	For (confirmed)
81		Core component ‘exercise training’. Strength training in frail COVID-19 patients should be included as normally indicated in CR programmes	3.90	1.61	For	4.10	1.34	For (confirmed)
82		Core component ‘exercise training’. Low-to-moderate intense endurance training should always be executed in COVID-19 patients as normally indicated in CR programmes	2.62	2.65	NC	2.62	2.65	NC
83		Core component ‘exercise training’. High-intensity interval training training should always be executed by COVID-19 patients as normally indicated in CR programmes	0.24	3.45	NC	0.14	3.42	NC
84		Core component ‘exercise training’. All COVID-19 patients should execute structured exercise for at least 3 days/week	3.19	2.50	For	3.19	2.50	For (confirmed)
85		Core component ‘exercise training’. All COVID-19 patients should maximize non-structured physical activity at home on daily basis	3.76	1.87	For	3.76	1.87	For (confirmed)
86		Core component ‘exercise training’. During structured exercise training, cardiac telemetry is advised to all COVID-19 patients	0.95	3.17	NC	0.76	3.91	NC
87		Core component ‘diet/nutritional counselling’. Nutritional intervention should be always particularly devoted to malnutrition as a consequence of prolonged immobilization and ventilatory support	2.95	2.54	For	3.14	2.46	For (confirmed)
88		In patients with history of COVID there is need to modify the core component ‘weight control management’	−0.71	4.04	NC	−0.62	3.96	NC
89		In patients with history of COVID there is need to modify the core component ‘lipid management’	−0.86	3.99	NC	−0.76	3.91	NC
90		In patients with history of COVID there is need to modify the core component ‘blood pressure management’	−1.33	3.83	NC	−1.33	3.72	NC
91		In patients with history of COVID there is need to modify the core component ‘smoking cessation’	−2.00	3.83	NC	−1.91	3.78	NC
92		Core component ‘psychosocial management’. Lifestyle and psychosocial management should always particularly focused on smoking cessation	3.00	2.94	For	3.27	2.62	For (confirmed)
93		Core component ‘psychosocial management’. Lifestyle and psychosocial management should always particularly focused on fear of infection	2.73	3.19	NC	2.73	3.19	NC
94		Core component ‘psychosocial management’. Lifestyle and psychosocial management should always particularly focused on fighting of fake news	3.36	2.26	For	3.36	2.26	For (confirmed)
95		Core component ‘psychosocial management’. Lifestyle and psychosocial management should always particularly focused on caregiver-limiting restrictive measures	2.82	2.44	For	2.82	2.44	For (confirmed)
96		Core component ‘psychosocial management’. Lifestyle and psychosocial management should always particularly focused on working resume	3.82	1.65	For	3.82	1.65	For (confirmed)
			Consensus rate: 32%			Consensus rate: 41%
Comments: As a general recommendation, in the delivery of core components consider simplified procedures to accelerate turnover During counselling, It's necessary empowering patients with COVID-19 and their caregivers Patient assessment needs to strictly evaluate history of contacts and symptoms During counselling of physical activity, add information on characteristics of open spaces, distances during exercise and self-protection If exercise testing is impossible other tools are needed to evaluate functional capacity Avoid face to face supervised exercise training as much as possible (consider video/telephone) During exercise training, respiratory techniques should be used with caution In some circumstances, more emphasis on physical activity could be given as often exercise training might not be possible During nutritional intervention, need to change body composition and improve malnutrition and muscle loss more than weight control A specific psychological intervention should be implemented: (i) assessment of patients to identify who survived severe and life-threatening experience and that are at risk of post-traumatic stress disorder and depression; (ii) psychological/psychotherapeutic programme to reduce emotional distress, to build resilience and to develop coping strategies During smoking cessation intervention, more control of smokers and so-called stoppers by measuring CO%Hb (to prevent further lung damage)
Open question: which are minimal structure-based metrics for CR programmes in the COVID-19 era?
97	There is no need to modify usual policies/recommendations for structure-based metrics		−1.71	3.86	NC	−1.77	3.78	NC
98	Residential CR facilities should have separated areas for confirmed COVID cases with regard to beds		3.55	2.91	For	3.61	2.86	For (confirmed)
99	Residential CR facilities should have separated areas for confirmed COVID cases with regard to investigation rooms		2.82	3.22	NC	2.83	3.14	NC
100	Residential CR facilities should have separated areas for confirmed COVID cases with regard to consultation areas		3.05	3.18	NC	3.04	3.11	NC
101	Residential CR facilities should have separated areas for confirmed COVID cases with regard to exercise laboratories		2.77	3.21	NC	2.83	3.14	NC
102	Residential CR facilities should have separated areas for confirmed COVID cases with regard to areas for exercise training		2.68	3.27	NC	2.74	3.21	NC
103	Residential CR facilities should have separated areas for suspected COVID cases with regard to beds		3.45	2.89	For	3.52	2.84	For (confirmed)
104	Residential CR facilities should have separated areas for suspected COVID cases with regard to investigation rooms		2.68	3.03	NC	2.70	2.96	NC
105	Residential CR facilities should have separated areas for suspected COVID cases with regard to consultation areas		2.91	3.10	NC	2.91	3.03	NC
106	Residential CR facilities should have separated areas for suspected COVID cases with regard to exercise laboratories		2.64	3.11	NC	2.70	3.05	NC
107	Residential CR facilities should have separated areas for suspected COVID cases with regard to exercise training		2.73	3.15	NC	2.78	3.09	NC
108	Residential CR facilities should have separated areas for COVID-free cases with regard to beds		2.67	3.77	NC	2.77	3.72	NC
109	Residential CR facilities should have separated areas for COVID-free cases with regard to investigation rooms		2.24	3.60	NC	2.27	3.52	NC
110	Residential CR facilities should have separated areas for COVID-free cases with regard to consultation areas		2.24	3.60	NC	2.27	3.52	NC
111	Residential CR facilities should have separated areas for COVID-free cases with regard to exercise laboratories		2.19	3.60	NC	2.27	3.53	NC
112	Residential CR facilities should have separated areas for confirmed COVID-frees with regard to areas for exercise training		2.33	3.31	NC	2.41	3.25	NC
113	When performing CPET and/or other aerosol-generating testing, approved filters for protecting workers and other patients from exposure to SARS-CoV-2 should be available		4.55	1.18	For	4.57	1.16	For (confirmed)
114	When performing CPET and/or other aerosol-generating testing, approved FFP-2 masks should be worn to protect workers and other patients from exposure to SARS-CoV-2 should be available		4.68	0.89	For	4.70	0.88	For (confirmed)
115	Floor space during exercise training is increased from 4 to at least 6 m² per patient		3.41	3.00	For	3.48	2.95	For (confirmed)
116	In the CR facility PPE for health care workers should be worn		4.17	1.50	For	4.21	1.47	For (confirmed)
117	A CR programme director to ensure proper organization and consistency of activities with national and institutional rules concerning SARS-CoV-2 infection prevention should be present		4.09	1.44	For	4.13	1.42	For (confirmed)
118	The multidisciplinary team (cardiologist, nurse, exercise specialist, dietitian, psychologist) should be preserved as much as possible		4.57	1.16	For	4.58	1.14	For (confirmed)
119	All members of the multidisciplinary should receive structured education on COVID-19 pathophysiology, clinical features, treatment, and prevention strategies		4.52	1.31	For	4.54	1.28	For (confirmed)
120	The job description for every profession should be updated with specific COVID-19 oriented features		3.65	2.52	For	3.71	2.48	For (confirmed)
121	The CR facility should provide dedicated operators and structured procedures facilitating contacts between patients and families in case of lockdown		4.22	1.38	For	4.25	1.36	For (confirmed)
			Consensus rate: 44%			Consensus rate: 44%
Comments: Efforts to maintain residential CR facilities as much as COVID-free as possible COVID-19 patients may also be treated separately at the end of the day followed by thorough disinfection Recovered COVID-19 patients with negative tests do not need to be separated Suspected COVID-19 patients should not participate until confirmed negative tests The strategy to test every patient scheduled for CPET, 1–2 days before CPET, using nasopharyngeal swab PCR could be considered When an aerosol-generating testing is performed no other patients should be present Consider that for frail patients filters may be heavy, due to resistance of this filters on breathing
Open question: which are minimal process-based metrics for CR programmes in the COVID-19 era?
122	There is no need to modify usual policies/recommendations for process-based metrics		−1.10	3.91	NC	−1.19	3.78	NC
123	The CR unit should provide fast testing and quarantine until test results are available in case of suspected or confirmed new emerging COVID-19 cases among the referred population		3.32	2.66	For	3.32	2.66	For (confirmed)
124	The suggested duration of CR programmes should be shortened (less than recommended 24 sessions), to increase the absolute number of CR programmes potentially delivered in a time unit		−0.77	3.75	NC	−0.68	3.67	NC
125	Patients coming for a CPET or other aerosol-generating procedures are first need to confirm to be COVID-19 negative		2.45	2.69	NC	2.41	2.65	NC
126	Plan at discharge and structured follow-up should be adapted to different phases of COVID-19 outbreak, in terms of timeline and diagnostic tools		3.95	1.40	For	3.95	1.40	For (confirmed)
127	CR facilities should offer a continuing help-desk to discharged patients and their caregivers on how to manage the relationship between COVID-10 and cardiovascular conditions		2.91	2.37	For	2.91	2.37	For (confirmed)
128	CR facilities with structured alternative models for delivering activities (tele-rehabilitation, facilitated home-based, web-based, supervised community-based, guided by digital health tools, etc.) should integrate the management of COVID-19 among programme contents		4.09	1.38	For	4.09	1.38	For (confirmed)
129	CR facilities without structured alternative models for delivering activities should implement initial forms of tele-rehabilitation, with integration of management of COVID-19 among programme contents		3.83	1.70	For	3.96	1.58	For (confirmed)
			Consensus rate: 62%			Consensus rate: 62%
Comments: Increase the rate of hybrid programmes for outpatient CR as much as possible Screening for COVID-19 before CPET depends on the region and pre-test probability of COVID-19 positive. If low clinical would be sufficient All CR processes need to be adjusted to minimize random infection by COVID-19 Patients recovered from COVID-19 infection and proved negative COVID-19 test should participate CR according to the accepted CR-indications but additionally should be integrated in multi-centre CR research programmes focusing on COVID-19 patients
Open question: which are quality indicators for CR programmes in the COVID-19 era?
130	There is no need to modify usual quality indicators in non-COVID patients		1.96	3.77	NC	1.87	3.72	NC
131	There is no need to modify usual quality indicators in COVID patients		0.91	3.96	NC	0.74	3.84	NC
132	% patients without history of COVID-19 eligible to CR referred after discharge to CR programme. The target should be maintained >80% as recommended by the 2020 position statement		2.77	3.16	NC	2.73	2.61	For (new)
133	% patients without history of COVID-19 eligible to CR referred after discharge to CR programme. The target should be reduced to <80% due to logistic problems during COVID-19 pandemia		0.05	4.03	NC	0.15	3.92	NC
134	% patients without history of COVID-19 eligible to CR, enrolled after discharge from COVID-19 units. The target should be >50% as recommended by the 2020 position statement		2.33	3.35	NC	2.29	3.32	NC
135	% patients without history of COVID-19 eligible to CR, enrolled after discharge from COVID-19 units. The target should be reduced to <50% due to logistic problems during COVID-19 pandemia		−0.95	3.62	NC	−0.85	3.53	NC
136	Patients without history of COVID-19, median waiting time from referral to start of CR. The target should be 14-28 days as recommended by the 2020 position statement		2.29	3.47	NC	2.29	3.47	NC
137	Patients without history of COVID-19, median waiting time from referral to start of CR. The target should be reduced to <14–28 days, motivated by the necessity to avoid prolonged lack of contacts with health care providers		−0.33	3.77	NC	−0.24	3.67	NC
138	Patients without history of COVID-19, % of CR uptake. The minimal target should be 24 sessions as recommended by the 2020 position statement		3.64	2.38	For	3.73	2.31	For (confirmed)
139	Patients without history of COVID-19, % of CR uptake. The minimal target should be <24 sessions to increase the absolute number of CR programmes potentially delivered in a time unit		−1.62	4.07	NC	−1.71	3.87	NC
140	% patients with history of COVID-19 eligible to CR referred after discharge to CR programme. The target should be maintained >80% as recommended by the 2020 position statement		2.05	3.73	NC	2.00	3.70	NC
141	% patients with history of COVID-19 eligible to CR referred after discharge to CR programme. The target should be reduced to <80% due to logistic problems during COVID-19 pandemia		−1.35	3.62	NC	−1.25	3.54	NC
142	% patients with history of COVID-19 eligible to CR, enrolled after discharge from COVID-19 units. The target should be >50% as recommended by the 2020 position statement		1.86	3.55	NC	1.86	3.55	NC
143	% patients with history of COVID-19 eligible to CR, enrolled after discharge from COVID-19 units. The target should be reduced to <50% due to logistic problems during COVID-19 pandemia		−1.05	3.64	NC	−0.95	3.56	NC
144	Patients with history of COVID-19, median waiting time from referral to start of CR. The target should be 14–28 days as recommended by the 2020 position statement		2.33	3.40	NC	2.33	3.40	NC
145	Patients with history of COVID-19, median waiting time from referral to start of CR. The target should be reduced to <14–28 days, motivated by the necessity to avoid prolonged lack of contacts with health care providers		−1.38	3.65	NC	−1.29	3.58	NC
146	Patients with history of COVID-19, % of CR uptake. The minimal target should be 24 sessions as recommended by the 2020 position statement		2.64	3.11	NC	2.64	3.11	NC
147	Patients with history of COVID-19, % of CR uptake. The minimal target should be <24 sessions to increase the absolute number of CR programmes potentially delivered in a time unit		−1.90	3.60	NC	−1.95	3.54	NC
148	% of CR drop-out due to de novo COVID-infection. The target should be <10%		3.00	3.13	NC	3.00	3.13	NC
149	% of patients with evaluation of functional capacity by standard exercise testing. The target should be >50%		2.86	3.17	NC	3.00	2.94	For (new)
150	% of patients with improvement of altered respiratory function and gas exchange following completion of CR. Target >90%		2.82	2.81	For	2.82	2.81	For (confirmed)
			Consensus rate: 10%			Consensus rate: 20%
Comments: As a general rule, targets should be based on region and restrictions Targets should consider non-responders also Targets need to be adjusted to the actual local risk and percentages of active COVID-19 cases in the population Needs of an European cardiac rehabilitation COVID-19 registry reflecting actual clinical situation

Including mean and standard deviation of the Likert scale. Consensus ‘for’ (mean score ≥2.5) or ‘against’ (mean score ≤2.5) each statement is indicated, while ‘NC’ (no consensus) indicates that consensus has not been reached (i.e. mean score between 2.4 and −2.4 or standard deviation crossing zero). The final consensus for each statement has been specified if confirmed or new, the latter indicating modification from round 2 to round 3. For each open question the consensus rate obtained at round 2 and 3 are provided. Comments have been edited for repetition, clarity, and anonymity, and served to present the whole picture of experts’ opinion.

ACS, acute coronary syndrome; CHF, chronic heart failure; CIED, cardiac implantable electronic device; CO%Hb, percentage of carboxyhaemoglobin; CPET, cardiopulmonary exercise testing; CR, cardiac rehabilitation; CV, cardiovascular; GPS, global positioning system; HTX, heart transplantation; ICU, intensive care unit; IMT, inspiratory muscle training; PCI, percutaneous coronary intervention; PPE, personal protective equipment; SCD, sudden cardiac death.