Table 1.
PPMO name | PPMO sequence (5′-3′) | PPMO target location in the SARS-CoV-2 genomea |
---|---|---|
NC | CCTCTTACCTCAGTTACAATTTATA | not applicable (negative control) |
5′END-1 | CCTGGGAAGGTATAAACCTTTAAT | 1–24 |
5′END-2 | TGTTACCTGGGAAGGTATAAACCTT | 5–29 |
TRS-1 | TTTTAAAGTTCGTTTAGAGAACAG | 59–82 |
TRS-2 | AAGTTCGTTTAGAGAACAGATCTAC | 53–77 |
AUGb | AGGCTCTCCATCTTACCTTTCGGT | 251–275 |
Based on GenBank NC_045512.
Bases targeting the AUG translation start site of SARS-CoV-2 1a/b polyprotein are in bold.