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Effect of NPD-1246 alone (in a dose of 20 or 10 mg/kg/day) or in combination with PZQ (10 mg/kg/day each) for 5 days treatment on (A) worm burden, (B) tissue egg load and (C) oogram pattern in S. mansoni-infected mice sacrificed 10 days post end of treatment. *Significantly different from infected control at p < 0.05. #Significantly different from PZQ group at p < 0.05. Numbers above columns and between parentheses represent percentage change from infected control group.
