Skip to main content
. Author manuscript; available in PMC: 2021 Oct 5.
Published in final edited form as: Chem Soc Rev. 2020 Oct 5;49(19):7167–7199. doi: 10.1039/d0cs00560f

Fig. 14.

Fig. 14

Small molecule targeting of RNA repeat expansions reduces aberrarnt repeat-associated non-ATG (RAN) translation. (A) Schematic of RAN translation of FMR1 due to r(CGG)exp in the 5′ UTR and C9orf72 due to r(G4C2)exp in intron 1. (B) Small molecules targeting r(CGG)exp and r(G4C2)exp inhibit RAN translation.