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Median GI50 (µM) values for subpanel cancer cell lines for conjugate 8a.
| Subpanel tumour cell line | 8a |
|
|---|---|---|
| MG-MID | Selectivity index | |
| Leukaemia | 1.33 | 2.33 |
| NSCL Cancer | 3.22 | 0.96 |
| Colon Cancer | 2.47 | 1.25 |
| CNS Cancer | 4.08 | 0.75 |
| Melanoma | 3.45 | 0.89 |
| Ovarian Cancer | 3.24 | 0.95 |
| Renal Cancer | 4.23 | 0.73 |
| Prostate Cancer | 2.85 | 1.08 |
| Breast Cancer | 3.09 | 1.00 |
| Full panel MG-MID | 3.10 | |
