Table 3.
Hypothetical RCC incidence in absence of hypertension and/or CKD among adults age 50 years or older by race and sex.
| Exposure | Sex/Race | SEER RCC incidence 2002-2006 |
Hypothetical RCC incidence in absence of exposurea(95%CI) |
|||
|---|---|---|---|---|---|---|
| USKC |
KPNC |
|||||
| Hypertension | Female | |||||
| White | 24.8 | 17.7 | (14.0, 21.5) | 18.0 | (16.2, 19.8) | |
| Black | 27.2 | 13.6 | (6.4, 20.8) | 16.4 | (10.3, 22.4) | |
| Male | ||||||
| White | 49.7 | 36.5 | (30.3, 42.6) | 40.3 | (37.7, 42.9) | |
| Black | 60.7 | 33.8 | (21.8, 45.7) | 46.9 | (33.9, 59.8) | |
| CKD | Female | |||||
| White | 24.8 | 24.7 | (24.3, 25.2) | 24.9 | (24.8, 25.0) | |
| Black | 27.2 | 24.9 | (23.2, 26.7) | 25.3 | (23.8, 26.8) | |
| Male | ||||||
| White | 49.7 | 49.4 | (48.9, 50.0) | 49.7 | (49.4, 50.0) | |
| Black | 60.7 | 55.0 | (51.7, 58.3) | 54.6 | (51.3, 57.9) | |
| CKD or hypertension | Female | |||||
| White | 24.8 | 17.4 | (13.8, 21.1) | 18.1 | (9.8, 21.2) | |
| Black | 27.2 | 13.3 | (6.3, 20.3) | 15.5 | (16.3, 19.8) | |
| Male | ||||||
| White | 49.7 | 36.3 | (30.2, 42.4) | 40.3 | (37.7, 42.9) | |
| Black | 60.7 | 30.9 | (20.5, 41.3) | 42.8 | (31.4, 54.3) | |
Abbreviations: USKC, US Kidney Cancer Study; KPNC, Kaiser Permanente Northern California; PAR, population attributable risk; CI, confidence interval; CKD, chronic kidney disease.
a
Renal cancer incidence rate per 100,000 per year in the absence of exposure = [SEER incidence rate at ages 50-79*(1-PAR%)] by race and sex; 95% CI’s were derived from the 95% CI’s of the PAR%. PAR% are presented in Table 2.