Figure 3:
Decision tree to apply criteria for in silico prediction tools, PP3 and BP4. PP3/BP4 will be applied for tRNA single nucleotide deletions based on MitoTIP only. P = pathogenic and N = neutral, per APOGEE algorithm.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.