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. 2020 Dec 4;99(49):e23560. doi: 10.1097/MD.0000000000023560

Table 2.

Association of rs4705342 and rs353292 in The Flanking Region of miR-143/145 with PTC Risk.

Polymorphisms Controls n = 347 (%) PTC n = 316 (%) Adjusted OR (95% CI) P value
rs4705342
 TT 168 (48.4) 188 (59.5) 1.00
 CT 148 (42.7) 115 (36.4) 0.70 (0.51–0.96) .03
 CC 31 (8.9) 13 (4.1) 0.37 (0.19–0.74) .003
 CT/CC 179 (51.6) 128 (40.5) 0.64 (0.47–0.87) .005
 T allele 484 (69.7) 491 (77.7) 1.00
 C allele 210 (30.3) 141 (22.3) 0.66 (0.52–0.85) .001
rs353292
 CC 246 (70.9) 214 (67.7) 1.00
 CT 97 (28.0) 97 (30.7) 1.15 (0.82–1.61) .42
 CT/TT 101 (29.1) 102 (32.3) 1.16 (0.83–1.61) .38
 C allele 589 (84.9) 525 (83.1) 1.00
 T allele 105 (15.1) 107 (16.9) 1.14 (0.85–1.53) .38

CI = confidence interval, OR = odds ratio, PTC = papillary thyroid carcinoma.

Adjusted by age and gender.