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. 2020 Dec 4;99(49):e23554. doi: 10.1097/MD.0000000000023554

Table 1.

Pan-cancer analysis of prognostic values of TPX2 for OS and RFS generated by the Kaplan--Meier Plotter database.

OS RFS
Cancer types HR 95% CI P HR 95% CI P
Bladder carcinoma 1.10 0.82–1.48 .509 0.88 0.43–1.78 .717
Breast cancer 1.20 0.87–1.65 .265 1.49 0.96–2.30 .070
Cervical squamous cell carcinoma 0.79 0.50–1.26 .323 0.97 0.45–2.09 .932
Esophageal adenocarcinoma 2.60 1.33–5.09 .004 1.24 0.17–9.09 .831
Esophageal squamous cell carcinoma 0.32 0.13–0.79 .010 0.48 0.18–1.30 .139
Head-neck squamous cell carcinoma 1.06 0.82–1.39 .645 0.72 0.34–1.52 .385
Kidney renal clear cell carcinoma 1.97 1.44–2.69 <.001 1.42 0.48–4.24 .525
Kidney renal papillary cell carcinoma 3.72 1.92–7.24 <.001 2.80 1.26–6.23 .009
Liver hepatocellular carcinoma 2.03 1.43–2.90 <.001 1.62 1.16–2.25 .004
Lung adenocarcinoma 1.59 1.18–2.13 .002 1.13 0.74–1.71 .569
Lung squamous cell carcinoma 0.90 0.69–1.18 .461 0.98 0.59–1.62 .936
Ovarian cancer 0.87 0.67–1.13 .307 0.87 0.61–1.24 .445
Pancreatic ductal adenocarcinoma 1.76 1.16–2.67 .007 3.02 1.23–7.40 .011
Pheochromocytoma and paraganglioma 4.05 0.46–35.39 .172 3.06 0.32–29.48 .308
Rectum adenocarcinoma 0.77 0.35–1.69 .517 1.66 0.30–9.09 .557
Sarcoma 1.38 0.92–2.06 .114 1.61 0.98–2.64 .057
Stomach adenocarcinoma 1.02 0.73–1.41 .915 0.84 0.44–1.62 .608
Testicular germ cell tumor 1.79 0.16–19.79 .629 1.78 0.81–3.90 .143
Thymoma 0.18 0.04–0.89 .020 / / /
Thyroid carcinoma 2.12 0.74–6.11 .154 3.43 1.38–8.54 .005
Uterine corpus endometrial carcinoma 1.91 1.24–2.94 .003 2.04 1.17–3.57 .011

95% CI = 95% confidence interval, HR = hazard ratio, OS = overall survival, RFS = relapse-free survival, TPX2 = targeting protein for Xenopus kinesin-like protein 2.

Bold values indicated statistical significance.