Table 3.

Correlation analysis between TPX2 and immune checkpoints expression.

	None		Purity			None		Purity
Expressed on tumor cells	Core	P	Core	P value	Expressed on immune cells	Core	P	Core	P
PDL1	0.060	.248	0.145	.006	PD1	0.230	<.001	0.338	<.001
PDL2	-0.070	.181	0.037	.497	CTLA4	0.256	<.001	0.376	<.001
CD80	0.245	<.001	0.380	<.001	CD28	0.106	.041	0.204	<.001
CD86	0.132	.011	0.291	<.001	LAG3	0.217	<.001	0.266	<.001
FGL1	-0.239	<.001	-0.193	<.001	CD226	-0.039	.457	0.061	.262
LGALS3	0.141	.006	0.188	<.001	TIGIT	0.202	<.001	0.334	<.001
CD112	0.037	.472	0.033	.545	CD96	0.050	.341	0.178	<.001
CD115	-0.040	.440	0.085	.113	BTLA	0.048	.359	0.182	<.001
HVEM	0.034	.520	0.061	.261	VISTA	-0.048	.376	0.020	.706
CEACAM1	-0.215	<.001	-0.196	<.001	TIM3	0.152	.003	0.315	<.001

Tumor purity is defined as percentage of malignant cells in a tumor tissue.

Bold values indicated statistical significance.