Table 3.
Indexes, median (IQR) | Total patients (N = 129) | Moderate patients (N = 89) | Severe/critical patients (N = 40) | P-value |
Blood routine | ||||
WBC (×109/L) | 4.56 (3.53–5.99) | 4.50 (3.43–5.76) | 4.85 (3.97–6.30) | .196 |
RBC (×1012/L) | 4.61 (4.19–5.08) | 4.64 (4.22–5.09) | 4.53 (4.12–5.07) | .430 |
HBG (g/L) | 138.00 (125.00–149.00) | 138.50 (125.00–149.50) | 137.00 (124.00–149.00) | .765 |
Platelet (×109/L) | 168.00 (146.00–214.00) | 178.00 (149.00–219.00) | 159.5 (134.0–193.25) | .081 |
Neutrophil count (×109/L)∗ | 3.34 (2.74–4.28) | 3.27 (2.59–4.15) | 3.37 (2.95–5.54) | .024 |
Lymphocyte count (×109/L) | 1.14 (0.83–1.56) | 1.27 (0.94–1.77) | 0.83 (0.60–1.16) | <.001 |
Monocytes count (×109/L)∗ | 0.27 (0.21–0.44) | 0.30 (0.19–0.48) | 0.21 (0.13–0.33) | .450 |
Eosinophil (×109/L)∗ | 0.01 (0.00–0.06) | 0.01 (0.00–0.05) | 0.00 (0.00–0.07) | .452 |
Basophil (×109/L)∗ | 0.01 (0.01–0.02) | 0.01 (0.01–0.02) | 0.01 (0.01–0.02) | .913 |
Neutrophils (%)∗ | 72.80 (61.40–83.60) | 68.80 (59.85–80.98) | 81.50 (63.90–89.45) | .006 |
Lymphocyte (%)∗ | 20.60 (13.00–29.60) | 22.20 (16.33–31.08) | 13.00 (8.00–28.75) | .005 |
Monocytes (%)∗ | 6.20 (2.90–7.90) | 6.55 (3.75–8.53) | 5.30 (1.85–6.50) | .094 |
Eosinophil (%)∗ | 0.10 (0.00–1.20) | 0.25 (0.00–1.23) | 0.00 (0.00–1.00) | .305 |
Basophil (%)∗ | 0.20 (0.20–0.30) | 0.20 (0.18–0.40) | 0.30 (0.20–0.30) | .789 |
PCV (%)∗ | 38.60 (36.70–44.50) | 38.50 (36.65–42.63) | 43.70 (36.85–44.95) | .346 |
MCV (fl)∗ | 89.90 (87.60–92.90) | 90.85 (88.35–94.05) | 89.70 (85.10–92.70) | .383 |
MCH (pg)∗ | 29.80 (28.80–30.90) | 29.90 (29.18–31.00) | 29.00 (27.70–30.85) | .962 |
MCHC (g/L)∗ | 333.00 (324.00–336.00) | 334.50 (325.25–336.50) | 325.00 (322.50–335.00) | .370 |
RDW-SD (fl)∗ | 39.90 (38.10–41.30) | 39.50 (37.95–41.50) | 41.00 (39.15–44.80) | .311 |
RDW-CV (%)∗ | 12.50 (11.90–12.90) | 12.05 (11.80–12.98) | 12.60 (12.55–14.05) | .125 |
PDW (%)∗ | 16.20 (14.20–16.30) | 16.05 (13.85–16.38) | 16.20 (13.75–16.30) | .156 |
MPV (fl)∗ | 10.30 (9.10–10.80) | 10.50 (9.10–10.83) | 10.00 (8.90–10.55) | .408 |
P-LCR (%)∗ | 27.50 (19.30–32.20) | 28.80 (19.23–32.65) | 25.30 (20.15–30.50) | .480 |
PCT (%)∗ | 0.20 (0.16–0.22) | 0.20 (0.13–0.23) | 0.20 (0.16–0.22) | .368 |
Inflammation index | ||||
CRP (mg/L) | 7.25 (1.96–19.07) | 5.82 (1.38–17.00) | 16.20 (6.28–43.52) | .010 |
Calcitonin (μg/L)∗ | 0.05 (0.03–0.09) | 0.04 (0.03–0.07) | 0.09 (0.05–1.15) | .028 |
Myocardial enzyme | ||||
α-HBDH (U/L) | 146.50 (130.00–189.00) | 142.00 (123.00–167.00) | 267.00 (167.00–373.00) | <.001 |
LDH (U/L) | 191.50 (164.25–323.75) | 183.00 (159.00–242.00) | 424.00 (231.00–679.00) | <.001 |
CK (U/L) | 66.00 (50.00–109.00) | 62.00 (48.00–98.00) | 85.00 (55.50–188.25) | .073 |
Liver function index | ||||
ALT (U/L) | 20.50 (14.83–30.88) | 19.00 (12.00–27.00) | 29.00 (18.00–47.90) | .001 |
AST (U/L) | 24.50 (19.00–34.10) | 22.00 (18.00–28.30) | 36.80 (26.70–61.50) | <.001 |
GGT (U/L) | 22.70 (15.80–40.80) | 22.00 (14.70–32.50) | 40.10 (20.00–57.00) | .004 |
Renal function index | ||||
Urea (mmol/L) | 3.94 (3.01–5.03) | 3.81 (2.94–4.95) | 4.82 (3.32–5.51) | .069 |
Creatinine (μmol/L) | 65.00 (54.30–75.00) | 61.80 (54.08–73.00) | 78.30 (56.00–94.00) | .028 |
Other index | ||||
D-dimer (μg/L) | 0.37 (0.24–0.67) | 0.31 (0.24–0.51) | 0.58 (0.38–0.79) | .004 |
α-HBDH = alpha-hydroxybutyric dehydrogenase, ALT = alanine transaminase, AST = aspartate aminotransferase, CK = Creatine Kinase, COVID-19 = Corona Virus Disease 2019, CRP = C-reactive protein, GGT = gamma-glutamyl transferase, HBG = hemoglobin, IQR = interquartile range, LDH = lactate dehydrogenase, MCV = mean corpuscular volume, MCH = mean corpuscular hemoglobin, MCHC = mean corpuscular-hemoglobin concentration, MPV = mean platelet volume, PCT = plateletcrit, PCV = packed cell volume, PDW = platelet distribution width, P-LCR = platelet large cell ratio, RBC = red blood cell, RDW-SD = red cell volume distribution width-standard deviation, RDW-CV = red cell volume distribution width standard deviation-coefficient of variation, WBC = white blood cell.
Only 29 COVID-19 patients recorded those indexes.