Table 6.
Indexes, median (IQR) | <40 years (N = 45) | 40-64 years (N = 66) | ≥65 years (N = 18) | P value |
Blood routine | ||||
WBC (×109/L) | 4.50 (3.23–6.19) | 4.50 (3.73–6.05) | 4.83 (3.53–5.73) | .822 |
RBC (×1012/L) | 4.75 (4.46–5.22) | 4.59 (4.19–5.06) | 4.16 (3.83–4.80) | .015 |
HBG (g/L) | 143.00 (129.00–150.00) | 138.00 (125.00–151.00) | 125.00 (122.00–148.00) | .286 |
Platelet (×109/L) | 189.00 (154.00–226.25) | 164.00 (144.00–200.00) | 162.00 (131.00–196.25) | .155 |
Neutrophil count (×109/L)∗ | 2.71 (1.65–4.70) | 3.34 (2.81–4.28) | 4.00 (3.81–5.40) | .002 |
Lymphocyte count (×109/L) | 1.37 (1.12–1.87) | 1.12 (0.77–1.44) | 0.87 (0.51–1.02) | <.001 |
Monocytes count (×109/L)∗ | 0.27 (0.14–0.44) | 0.30 (0.21–0.44) | 0.21 (0.16–0.42) | .837 |
Eosinophil (×109/L)∗ | 0.01 (0.00–0.03) | 0.00 (0.00–0.08) | 0.01 (0.01–0.04) | .873 |
Basophil (×109/L)∗ | 0.00 (0.00–0.00) | 0.02 (0.01–0.02) | 0.01 (0.01–0.02) | .784 |
Neutrophils (%)∗ | 67.50 (48.60–83.65) | 72.80 (55.20–81.50) | 75.50 (71.35–83.55) | .044 |
Lymphocyte (%)∗ | 23.00 (11.30–44.10) | 20.20 (13.00–35.50) | 22.00 (13.20–22.20) | .042 |
Monocytes (%)∗ | 6.50 (3.95–8.25) | 6.20 (4.10–7.90) | 2.90 (2.45–6.70) | .356 |
Eosinophil (%)∗ | 0.40 (0.00–0.85) | 0.00 (0.00–1.20) | 0.10 (0.05–0.45) | .716 |
Basophil (%)∗ | 0.20 (0.15–0.35) | 0.30 (0.20–0.40) | 0.20 (0.15–0.25) | .189 |
PCV (%)∗ | 39.00 (37.45–40.50) | 38.40 (36.70–44.60) | 38.10 (37.20–41.95) | .724 |
MCV (fl)∗ | 92.90 (86.45–93.55) | 89.70 (88.60–92.80) | 91.80 (88.75–93.55) | .522 |
MCH (pg)∗ | 29.60 (29.00–30.80) | 30.00 (28.80–31.50) | 29.70 (28.60–30.50) | .703 |
MCHC (g/L)∗ | 333.00 (322.50–335.00) | 335.00 (325.00–339.00) | 323.00 (322.00–326.00) | .665 |
RDW-SD (fl)∗ | 39.60 (38.45–40.60) | 39.90 (37.40–41.30) | 42.10 (40.75–45.20) | .092 |
RDW-CV (%)∗ | 12.00 (11.85–12.65) | 12.60 (11.80–12.90) | 12.60 (12.40–14.00) | .045 |
PDW (%)∗ | 15.90 (12.95–17.40) | 16.00 (12.80–16.30) | 16.30 (16.25–16.30) | .801 |
MPV (fl)∗ | 10.70 (9.10–10.95) | 10.00 (9.00–10.80) | 10.30 (9.55–11.80) | .535 |
P-LCR (%)∗ | 31.60 (18.90–33.70) | 25.30 (19.10–31.90) | 27.50 (24.35–37.05) | .642 |
PCT (%)∗ | 0.17 (0.12–0.21) | 0.21 (0.16–0.24) | 0.20 (0.17–0.22) | .493 |
Inflammation index | ||||
CRP (mg/L) | 5.03 (0.73–15.14) | 11.70 (3.45–19.60) | 6.60 (3.17–35.19) | .120 |
Calcitonin (μg/L)∗ | 0.04 (0.03–0.04) | 0.05 (0.03–0.09) | 0.09 (0.08–1.13) | .011 |
Myocardial enzyme | ||||
α-HBDH (U/L) | 130.00 (105.50–141.50) | 166.00 (141.25-196.75) | 170.50 (151.25–347.75) | <.001 |
LDH (U/L) | 165.00 (146.00–188.00) | 210.00 (172.75–318.75) | 365.00 (191.00–510.00) | <.001 |
CK (U/L) | 57.00 (42.00–81.00) | 74.00 (50.50–111.50) | 108.50 (55.50–208.25) | .014 |
Liver function index | ||||
ALT (U/L) | 17.80 (10.00–25.00) | 22.00 (15.25–32.75) | 26.60 (16.95–36.80) | .061 |
AST (U/L) | 20.00 (17.00–27.80) | 26.00 (20.50–34.60) | 32.00 (22.85–42.80) | .008 |
GGT (U/L) | 19.40 (14.00–29.50) | 30.00 (17.00–45.00) | 22.00 (16.90–40.95) | .028 |
Renal function index | ||||
Urea (mmol/L) | 3.80 (2.71–4.89) | 3.89 (3.00–5.04) | 5.08 (3.79–11.20) | .059 |
Creatinine (μmol/L) | 59.45 (51.25–74.25) | 66.00 (56.00–75.75) | 64.80 (54.18–76.98) | .566 |
Other index | ||||
D-dimer (μg/L) | 0.27 (0.22–0.39) | 0.41 (0.25–0.74) | 0.53 (0.34–1.36) | .004 |
α-HBDH = alpha-hydroxybutyric dehydrogenase, ALT = alanine transaminase, AST = aspartate aminotransferase, CK = Creatine Kinase, COVID-19 = Corona Virus Disease 2019, CRP = C-reactive protein, GGT = gamma-glutamyl transferase, HBG = hemoglobin, IQR = interquartile range, LDH = lactate dehydrogenase, MCV = mean corpuscular volume, MCH = mean corpuscular hemoglobin, MCHC = mean corpuscular-hemoglobin concentration, MPV = mean platelet volume, PCT = plateletcrit, PCV = packed cell volume, PDW = platelet distribution width, P-LCR = platelet large cell ratio, RBC = red blood cell, RDW-SD = red cell volume distribution width-standard deviation, RDW-CV = red cell volume distribution width standard deviation-coefficient of variation, WBC = white blood cell.
Only 29 COVID-19 patients recorded those indexes.