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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Genet Epidemiol. 2020 Mar 29;44(6):629–641. doi: 10.1002/gepi.22292

Table 1.

Lifestyle exposure variables used in this study

Lifestyle exposure Variable Original variable(s) in FHS Modification/Remark Values*
Smoking 1. Smk_now Smoke regularly in the past year? 0: former and never smokers
1: current smokers only
Smk_now (0)
Smk_now (1)
2. Smk_ever Ever smoke cigarettes regularly? 0: never smokers only
1: former and current smokers
Smk_ever (0)
Smk_ever (1)

Alcohol 3. Alc_heavy Total number of alcoholic drinks/week 0: consumed 0 or 1 – 7 drinks/week Alc_heavy (0)
1: consumed > 7 drinks/week Alc_heavy (1)
4. Alc_moderate Total number of alcoholic drinks/week 0: consumed 0 or > 7 drinks/week Alc_moderate (0)
1: consumed 1 – 7 drinks/week Alc_moderate (1)

Education 5. Edu_somecol Post-secondary education? (Education level in categories/years) 0: if no post-secondary education (i.e., no schooling, grades 1 – 11, high school grad or GED or years of education ≤ 12). Edu_somecol (0)
1: if there is some form of post-secondary education (i.e., some college, technical school, associate degree, bachelors degree, or graduate/professional degree or years of education ≥ 13) Edu_somecol (1)
6. Edu_gradcol Graduate college? (Education level in categories/years) 0: if no graduate college degree (i.e., all the levels below bachelors degree defined above). Edu_gradcol (0)
1: if bachelors/graduate/professional degree or ≥ 16 years of education. Edu_gradcol (1)

Physical activity 7. PA_active Hours spent in moderate activity, and hours spent in heavy activity Sum of time spent in moderate activity and twice the time spent in heavy activity, then split by lower quartile (Q1=3);
0: ≥ 3 hours of time equivalent in moderate and heavy physical activity
1: < 3 hours of time equivalent in moderate and heavy physical activity.
PA_active (0)
PA_active (1)
*

Value assignment across variables was done in one of two ways; for Smk_now, Smk_ever, Alc_heavy and PA_active, 0 was assigned to the unexposed group and 1 to the exposed group, while for Alc_moderate, Edu_somecol and Edu_gradcol, the unexposed group was assigned a value of 1 and the exposed group a value of 0.