Table 5.
P-values for the genetic effect using refined main effects models, which omits the interaction term but adjusts for the marginal effect of the LRS (Model (2)) or the marginal effects of the four component lifestyle variables (Model (3)).
| Chr:position† | SNP | BP trait | Exposure | Model 2 | Model 3 |
|---|---|---|---|---|---|
| 2:134312960 | rs1368091 | DBP | DLRS | 7.59E-01 | 8.37E-01 |
| 3:123923233 | rs7652065 | SBP | DLRS | 9.56E-01 | 9.13E-01 |
| 3:123923922 | rs1444768 | SBP | DLRS | 9.54E-01 | 9.11E-01 |
| 3:123927014 | rs880000 | SBP | DLRS | 8.75E-01 | 8.34E-01 |
| 3:123930542 | rs1444757 | SBP | DLRS | 8.87E-01 | 8.49E-01 |
| 3:143028187 | rs17636599 | SBP | QLRS | 1.20E-02 | 1.42E-02 |
| 4:180139179 | rs10520420 | DBP | DLRS | 9.21E-02 | 8.20E-02 |
| 4:180151019 | rs4146838 | DBP | DLRS | 8.77E-02 | 7.75E-02 |
| 4:180164081 | rs969219 | DBP | DLRS | 8.20E-02 | 7.21E-02 |
| 4:180178378 | rs11131920 | DBP | DLRS | 5.01E-02 | 4.25E-02 |
| 4:180179576 | rs11131921 | DBP | DLRS | 5.03E-02 | 4.27E-02 |
| 7:158848821 | rs3793217 | DBP | QLRS | 5.71E-02 | 7.41E-02 |
| 8:25374910 | rs2012485 | SBP | QLRS | 8.19E-01 | 7.91E-01 |
| 8:54274100 | rs7001769 | SBP | QLRS | 3.36E-06 | 5.78E-06 |
| 8:54277247 | rs7465458 | SBP | QLRS | 3.36E-06 | 5.61E-06 |
| 11:11395489 | rs10047474 | DBP | QLRS | 1.06E-03 | 1.64E-03 |
| 11:49202187 | rs7124497 | SBP | DLRS | 1.92E-04 | 1.22E-04 |
| 12:133441378 | rs4303268 | SBP | QLRS | 7.20E-01 | 6.04E-01 |
| 15:64315336 | rs12442060 | SBP | DLRS | 6.93E-01 | 8.14E-01 |
| 15:64316458 | rs172995 | SBP | DLRS | 6.30E-01 | 7.83E-01 |
| 18:30053150 | rs11081767 | DBP | QLRS | 6.21E-01 | 6.10E-01 |
†
Chr:position: based on human genome build 37.