Table 2. Hazard ratios and 95% confidence intervals of breast cancer in relation to sense of coherence measured at baseline.
| SoC | 1000 PYs | Event (IR) | Model 1* | Model 2† |
|---|---|---|---|---|
| In three categories‡ | ||||
| Weak SoC | 83 | 251 (3.0) | 1.00 | 1.00 |
| Moderate SoC | 83 | 264 (3.2) | 1.05 (0.88–1.25) | 1.00 (0.84–1.19) |
| Strong SoC | 74 | 256 (3.5) | 1.15 (0.97–1.37) | 1.08 (0.90–1.29) |
| Per SD increase§ | 240 | 771 (3.2) | 1.11 (1.03–1.20) | 1.08 (1.00–1.17) |
Abbreviations: PYs, person-years; IR, incidence rate per 1000 person-years; SoC, sense of coherence; SD, standard deviation.
*: Estimates were not adjusted for any covariate. †: Estimated were adjusted for sociodemographic factors (age, ancestry, education) and lifestyle factors (body mass index, smoking, alcohol consumption, physical activity), and known risk factors for breast cancer including reproductive and hormonal factors (age at menarche, age at first birth, No. of pregnancies, No. of births, use of contraceptives, use of hormone replacement therapy, menopausal status), as well as family history of breast cancer, benign breast disorders, other malignancies, and breast density.
‡: Total SoC score at baseline was calculated and categorized as weak, moderate, and strong according to tertile distribution of all women. §: SoC was treated as a continuous variable after standardization using z-score method.