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. 2020 Nov 23;9:e61469. doi: 10.7554/eLife.61469

Table 2. Hazard ratios and 95% confidence intervals of breast cancer in relation to sense of coherence measured at baseline.

SoC 1000 PYs Event (IR) Model 1* Model 2
In three categories
Weak SoC 83 251 (3.0) 1.00 1.00
Moderate SoC 83 264 (3.2) 1.05 (0.88–1.25) 1.00 (0.84–1.19)
Strong SoC 74 256 (3.5) 1.15 (0.97–1.37) 1.08 (0.90–1.29)
Per SD increase§ 240 771 (3.2) 1.11 (1.03–1.20) 1.08 (1.00–1.17)

Abbreviations: PYs, person-years; IR, incidence rate per 1000 person-years; SoC, sense of coherence; SD, standard deviation.

*: Estimates were not adjusted for any covariate. : Estimated were adjusted for sociodemographic factors (age, ancestry, education) and lifestyle factors (body mass index, smoking, alcohol consumption, physical activity), and known risk factors for breast cancer including reproductive and hormonal factors (age at menarche, age at first birth, No. of pregnancies, No. of births, use of contraceptives, use of hormone replacement therapy, menopausal status), as well as family history of breast cancer, benign breast disorders, other malignancies, and breast density.

: Total SoC score at baseline was calculated and categorized as weak, moderate, and strong according to tertile distribution of all women. §: SoC was treated as a continuous variable after standardization using z-score method.