Table 3. Hazard ratios and 95% confidence intervals of breast cancer subtypes in relation to sense of coherence measured at baseline.

Subtypes*	Weak SoC†			Moderate SoC			Strong SoC
	1000 PYs	Event (IR)	HR	1000 PYs	Event (IR)	HR (95% CI)‡	1000 PYs	Event (IR)	HR (95% CI)‡
Luminal A	83	105 (1.3)	Ref.	83	99 (1.2)	0.91 (0.69–1.20)	74	100 (1.4)	1.05 (0.79–1.39)
Luminal B1	83	17 (0.2)	Ref.	83	22 (0.3)	1.23 (0.65–2.34)	74	12 (0.2)	0.63 (0.30–1.34)
Luminal B2	83	12 (0.1)	Ref.	83	14 (0.2)	1.28 (0.58–2.80)	74	15 (0.2)	1.47 (0.67–3.23)
Triple-negative	83	9 (0.1)	Ref.	83	15 (0.2)	1.52 (0.66–3.50)	74	6 (0.1)	0.71 (0.24–2.04)
HER2-enriched	83	9 (0.1)	Ref.	83	8 (0.1)	0.78 (0.30–2.06)	74	7 (0.1)	0.82 (0.30–2.28)
Unclassified	83	99 (1.2)	Ref.	83	106 (1.3)	0.99 (0.75–1.31)	74	116 (1.6)	1.23 (0.93–1.62)

Abbreviations: PYs, person-years; IR, incidence rate per 1000 person-years; SoC, sense of coherence.

^*: Breast cancer subtypes were classified based on estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). Luminal A: ER+, PR+, HER2-; Luminal B1: ER+, PR-, HER2-; Luminal B2: ER+, HER2+; Triple-negative: ER-, PR-, HER2-; HER2-enriched: ER-, PR-, HER2+; the rest were unclassified, mostly because of undetermined HER2 status.

^†: A total SoC score at baseline was calculated and categorized according to tertiles in all women: weak, moderate, and strong. ^‡: Estimates were adjusted for sociodemographic factor (age, ancestry, education), lifestyle factors (body mass index, smoking, alcohol consumption, physical activity), and known risk factors for breast cancer including reproductive and hormonal factors (age at menarche, age at first birth, No. of pregnancies, No. of births, use of contraceptives, use of hormone replacement therapy, menopausal status), as well as family history of breast cancer, benign breast disorders, other malignancies, and breast density.