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. 2020 Nov 19;11:558874. doi: 10.3389/fendo.2020.558874

Figure 2.

Figure 2

Effect of DIP on body weight and fat accumulation in HFD fed mice. HFD-induced obese mice were treated with 200 µl of DIP at various doses for 4 weeks (n = 8 each group). (A) Effects of DIP administration on body weight (g), (B) body weight gain (%), (C) body weight gain (g), (D) epididymal fat (g), (E) subcutaneous fat (g), and (F) liver weight are presented in the above panels. Data are expressed as mean ± SEM. Body weight differences in (A, B) were analyzed using two-way ANOVA Bonferroni post hoc test. ##p < 0.01, ###p < 0.001, ####p < 0.0001 HFD group vs HFD+DIP(L) group; ****p < 0.0001 HFD group vs HFD + DIP(H). One-way ANOVA Bonferroni post hoc was employed to determine statistical differences in (C–F). ##p < 0.01, ####p < 0.0001 HFD group vs control group; **p < 0.01, ***p < 0.001, ****p < 0.0001 HFD group vs HFD + DIP(L) and HFD + DIP(H) groups.