TABLE 1.

Diagnostic performance of Class One microbials.

Name	Sensitivity%	Specificity%	AUC	Algorithm	Sample	Case	Region	References
Fn	73.1	90.8	0.860	Relative Abundance	Feces	490	China	Wong et al., 2017a
Pa	56.7	86.3	0.720	Logistic regression	Feces	390	China	Wong et al., 2017a
Pm	45.2	97.1	0.730	Logistic regression	Feces	390	China	Wong et al., 2017a
Gm	39.0	76.0	0.622	Relative Abundance	Feces	333	Spain	Malagón et al., 2019
Ps	53.0	76.0	0.710	Relative Abundance	Feces	333	Spain	Malagón et al., 2019
Bf	33.0	0.76	0.571	Relative Abundance	Feces	333	Spain	Malagón et al., 2019
pks	56.4	82.0	NA	Relative Abundance	Feces	238	Sweden	Eklöf et al., 2017
Fp	81.8	62.6	0.741	Abundance Rate	Feces	549	China	Rezasoltani et al., 2018
Bb	90.4	76.4	0.870	Abundance Rate	Feces	549	China	Rezasoltani et al., 2018
Cs	73.3	66.1	0.736	logistic regression	Feces	781	China	Xie et al., 2017
Ap	NA	NA	NA	Relative abundance	Feces	146	Meta	Yachida et al., 2019
Gl	NA	NA	NA	Relative abundance	Mucosa	207	China	Nakatsu et al., 2015
m3	62.1	79.0	0.741	Relative Abundance	Feces	1012	China	Liang et al., 2019
Bd	NA	NA	NA	Relative abundance	Feces	179	French	Sobhani et al., 2011
afaC	NA	NA	NA	Relative abundance	Tissue	55	South Africa	Viljoen et al., 2015
Akk	NA	NA	NA	Relative abundance	Feces	112	China	Wang et al., 2020
Cb	NA	NA	0.930	Random forest	Feces	60	China	Yang et al., 2020

NA, non-available; Meta, meta-analysis; Gemella morbillorum (Gm); Bacteroides fragilis (Bf); pks + clbA + Escherichia coli (pks); Clostridium symbiosum (Cs); Atopobium parvulum (Ap); Granulicatella (Gl); Bacteroides (Bd); afaC-positive E. coli (afaC).