Table 6.
Odds ratio of having underlying malaria when presenting with diarrhoea, compared to “controls.”
References | Origin | Patient(s) | Cases—with diarrhoea | “Controls”—without diarrhoea | Odds ratio (95% CI) | |||||
---|---|---|---|---|---|---|---|---|---|---|
Number with diarrhoea, n | Malaria positive, n (%) | Species | Control recruitment | Fever? | Number of diarrhoea negative controls, n | Controls with malaria, n (%) | ||||
Laurentz and Manoempil (63) | Indonesia | Children | 821 | 150 (18.3%) | P. falciparum | Hospital | 69% febrile | 1,192 | 271 (22.7%) | 0.76 (0.61, 0.95), p = 0.02 |
Sodeinde et al. (29) | Nigeria | Children (median 15 mo) | 522 | 68 (13%) | P. falciparum | Hospital | 75% febrile | 313 | 56 (17.9%) | 0.69 (0.46, 1.01), p = 0.056 |
Sodemann et al. (64) | Guinea-Bissau | Children (median 19 mo) | 297 | 80 (26.9%) | P. falciparum | Community | 15% febrile, via maternal reporting | 297 | 72 (24.2%) | 1.15 (0.80, 1.66), p = 0.45 |
Ashie et al. (65) | Ghana | Children (<5 y) | 240 | 22 (9.2%) | Not stated but likely to be predominantly P. falciparum | Hospital | Not reported | 107 | 1 (0.9%) | 10.7 (1.42, 80.4), p = 0.02 |