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. 2020 Nov 20;11:584460. doi: 10.3389/fgene.2020.584460

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Copyright © 2020 Shen, Wang, Shao, Wu, Li, Che and Ni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Establishment of cisplatin-induced acute kidney injury model in C57 mouse. (A) Analysis of Scr level in mice following different treatments. Error bars represent the standard deviation. ***p < 0.001, Student’s t-test. (B) Analysis of BUN level in mice following different treatments. Error bars represent the standard deviation. *p < 0.05, ***p < 0.001, Student’s t-test. (C) Represents the image of hematoxylin and eosin staining in kidney (black arrows indicating the injury). (D) Score for characteristic histologic signs of renal injury. **p < 0.01, ***p < 0.001, Student’s t-test.