Table 3.
Relationship between change in HAMD and baseline FA in ESC/MEM and ESC/PBO.
| FA | Left | Right | ||||
|---|---|---|---|---|---|---|
| Interaction group x FA | ESC+MEM | ESC+PBO | Interaction group x FA | ESC+MEM | ESC+PBO | |
| HAMD | ||||||
| ALIC | F(1, 18) = 4.66, p = 0.04* | T = −3.63, p = 0.002; r = −0.77 | T = −0.56, p = 0.58 | F(1, 18)= 7.7, p = 0.01* | T = −5.11, p ≤ 0001; r = −0.78 | T = −0.76, p = 0.45 |
| PLIC | F(1, 18) = 7.71, p = 0.01 | T = −2.73, p = 0.01; r = −0.51 | T = 1.35, p = 0.19 | F(1, 18)= 5.76, p = 0.03* | T = −1.84, p = 0.08; r = −0.31 | T = 1.09, p = 0.29 |
| CGC | F(1, 18) = 0.34, p = 0.56 | F(1, 18)= 2.11, p = 0.16 | ||||
| IFO | F(1, 18) = 4.65, p = 0.04* | T = −2.57, p = 0.02; r = −0.59 | T = 0.23, p = 0.82 | F(1, 18) = 4.69, p = 0.04* | T = −3.58, p = 0.002; r = −0.63 | T = 0.18, p = 0.86 |
| SFO | F(1, 18) = 0.17, p = 0.69 | F(1, 18)= 8.48, p = 0.009** | T = −3.63, p = 0.002; r = −0.75 | T = −0.04, p = 0.97 | ||
| SLF | F(1, 18) = 1.49, p = 0.24 | F(1, 18)= 3.31, p = 0.09 | ||||
| FX | F(1, 18) = 0.24, p = 0.63 | F(1, 18)= 0.01, p = 0.94 | ||||
| FX Body | Interaction: F(1, 18) = 0.06, p = 0.80 | |||||
| GCC | Interaction: F(1, 18) = 0.13, p = 0.73 | |||||
The results stem from the rank-based general linear models including the treatment group, FA and the interaction between group and FA as the predictors, while controlling for the respective baseline score, age, sex and scanner.
HAMD, Hamilton Depression Scale.
Significant after FDR correction.