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. 2020 Nov 17;11:598845. doi: 10.3389/fphys.2020.598845

Figure 4.

Figure 4

The model reproduces estradiol-mediated inhibition of PG activity following high doses of CORT. (A) High exogenous CORT over 48 h does not affect the PG dynamics in OVX mice. (B) In the presence of estradiol, high CORT doses temporarily reduce PG activity in OVX mice.