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. 2020 Nov 20;10:590861. doi: 10.3389/fonc.2020.590861

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Copyright © 2020 Zhuo, Chen, Yang, Zhang, Tang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of gliomas subclasses using NMF consensus clustering in the ferroptosis set. (A) Flow chart of the study. (B) NMF clustering using 84 ferroptosis-related genes. Patients were divided into cluster 1 and cluster 2. (C) t-SNE analysis supported the stratification into two gliomas subclasses. (D) Heat map of two clusters defined by the ferroptosis-related genes expression. (E) Survival analysis of patients in Clusters 1 and 2 in CGGA cohort.