(a) Insulin signaling pathway
| Gene ID | Gene symbol | Log2FC | P adj | Description |
|---|---|---|---|---|
| Upregulated genes | ||||
| ENSGALG00000007919 | EIF4E2 | 0.20281 | 0.005635 | Translation initiation factor eIF-4e |
| ENSGALG00000006418 | PDPK1 | 0.21168 | 0.00028551 | Tyrosine-protein kinase, catalytic domain |
| ENSGALG00000001267 | MAP2K2 | 0.18059 | 0.020795 | Serine-threonine/tyrosine-protein kinase catalytic domain |
| ENSGALG00000002485 | PHKG1 | 0.21809 | 0.0065997 | Phosphorylase kinase, gamma catalytic subunit |
| ENSGALG00000007373 | PRKAB1 | 0.20238 | 0.0012886 | Immunoglobulin E-set |
| ENSGALG00000026692 | N-RAS | 0.1801 | 0.0062565 | Small GTP-binding protein domain |
| ENSGALG00000010440 | MKNK1 | 0.3733 | 0.002099 | Tyrosine-protein kinase, catalytic domain |
| ENSGALG00000001678 | PRKAB2 | 0.26435 | 0.01324 | Association with the SNF1 complex (ASC) domain |
| ENSGALG00000006885 | H-RAS | 0.32313 | 2.3544E − 10 | Small GTPase superfamily, Rab type |
| ENSGALG00000027275 | PPP1R3B | 0.31903 | 4.6517E − 08 | Putative phosphatase regulatory subunit |
| Downregulated genes | ||||
| ENSGALG00000002583 | PIK3CD | -0.41721 | 0.0039568 | Phosphoinositide 3-kinase, accessory (PIK) domain |
| ENSGALG00000007023 | PRKAR2A | -0.3031 | 0.0003467 | cAMP-dependent protein kinase regulatory subunit |
| ENSGALG00000010709 | AKT3 | -0.28405 | 0.049919 | Pleckstrin homology domain |
| ENSGALG00000027188 | SREBP-1 | -0.32066 | 0.026855 | Tumor necrosis factor-like domain |
| ENSGALG00000005198 | RPS6KB1 | -0.31356 | 0.0034049 | Tyrosine-protein kinase, catalytic domain |