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. 2020 Nov 28;54:319–327. doi: 10.1016/j.breast.2020.11.018

Table 6.

Sensitivity analyses of chemotherapy receipt on breast cancer-specific mortality using the Cox regression model and the competing-risks model (SEER database).

Variables Cox regression model
Competing-risks model
HR 95%CI P sdHR 95%CI P
Years 20042010
Intermediate RS (n = 2967)
 No chemotherapy 1 1
 Chemotherapy 0.824 0.513–1.325 0.425 1.009 0.395–2.578 0.985
High RS (n = 856)
 No chemotherapy 1 1
 Chemotherapy 0.923 0.641–1.329 0.668 1.092 0.665–1.791 0.728
Years 20112012
Intermediate RS (n = 2092)
 No chemotherapy 1 1
 Chemotherapy 2.111 0.979–4.552 0.057 4.204 0.966–18.289 0.056
High RS (n = 622)
 No chemotherapy 1 1
 Chemotherapy 0.717 0.355–1.449 0.355 0.848 0.319–2.253 0.741
Aged 6569 years
Intermediate RS (n = 2816)
 No chemotherapy 1 1
 Chemotherapy 1.077 0.610–1.901 0.799 1.94 0.648–5.811 0.236
High RS (n = 795)
 No chemotherapy 1 1
 Chemotherapy 1.075 0.659–1.753 0.773 1.602 0.818–3.138 0.17
Aged 7074 years
Intermediate RS (n = 1405)
 No chemotherapy 1 1
 Chemotherapy 0.739 0.319–1.710 0.48 1.511 0.409–5.584 0.536
High RS (n = 432)
 No chemotherapy 1 1
 Chemotherapy 0.597 0.313–1.138 0.117 0.557 0.226–1.370 0.203
Aged > 74 years
Intermediate RS (n = 838)
 No chemotherapy 1 1
 Chemotherapy 1.397 0.634–3.078 0.407 1.187 0.141–10.006 0.875
High RS (n = 251)
 No chemotherapy 1 1
 Chemotherapy 0.767 0.403–1.461 0.42 0.793 0.272–2.311 0.671

CI, confidence interval; HR, hazard ratio; RS, recurrence score; sdHR, sub-distribution hazard ratio.