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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Cogn Affect Behav Neurosci. 2020 Dec;20(6):1173–1183. doi: 10.3758/s13415-020-00824-2

Figure 2: Both mAChR and nAChR antagonists attenuated physostigmine-induced immobility.

Figure 2:

(n=16-18 male mice per group) Physostigmine-induced increases in Forced Swim Test immobility was attenuated in animals pretreated with 0.065 mg/kg of the mAChR antagonist scopolamine (SCP, (F(2,47)=5.274, p=0.009) and 0.56 mg/kg of the nAChR antagonist mecamylamine (MEC, F(2,53)=4.622, p=0.014). Statistical effects were queried using ANOVA with photoperiod, and drug treatment as factors. Hypothesized a priori effects of physostigmine were queried using specific one-way ANOVA. Data presented as individual data points, mean, ±S.E.M., *=p<0.05 as indicated.