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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Cogn Affect Behav Neurosci. 2020 Dec;20(6):1173–1183. doi: 10.3758/s13415-020-00824-2

Figure 3: ACh antagonists attenuated SAP-induced FST immobility.

Figure 3:

Elevated Forced Swim Test (FST) immobility induced by 2 week exposure to short active photoperiod was blocked by treatment with 0.03 mg/kg scopolamine. Short active photoperiod significantly increased FST immobility (A, F(1,63)=6.492, p=0.013 & B F(1,136)=4.320, p=0.046), which was significantly attenuated by mAChR antagonist scopolamine (A, F(1,136)=1.80, p=0.04 ). The nAChR antagonist mecamylamine did not reduce immobility at 0.56 mg/kg dose in this experiment. Statistical effects in these data were queried using ANOVA with, photoperiod, and drug treatment as factors. Data presented as individual data points, mean, ±S.E.M., #=p<0.10, *=p<0.05.