Table 2.
Patient, tumor, and treatment characteristics
Age | Median 64 y, (range, 33-88) |
Male | 9 |
Female | 7 |
Site | |
Extremity | 14 |
Upper extremity | 4 |
Lower extremity | 10 |
Trunk | 2 |
Histology | |
Dedifferentiated liposarcoma | 1 |
CIC-rearranged sarcoma | 1 |
Extraskeletal myxoid chondrosarcoma | 1 |
Myxofibrosarcoma | 4 |
Myxoid liposarcoma | 3 |
Pleomorphic leiomyosarcoma | 1 |
Synovial sarcoma | 2 |
Undifferentiated pleomorphic/spindle cell sarcoma | 3 |
Grade∗ | |
Grade 2 | 8 |
Grade 3 | 3 |
Greatest tumor dimension on final pathology | |
≤5 cm | 3 |
>5 cm and ≤10 cm | 9 |
>10 cm and ≤15 cm | 3 |
>15 cm | 1 |
Metastatic at diagnosis | 4 |
PTV size | Median 485 cm3 (range, 56-4353) |
Radiation technique | |
Step and shoot IMRT | 3 |
VMAT | 16 |
Radiation dose | |
27.5 Gy/5 fx | 1 |
30 Gy/5 fx | 14 |
40 Gy/5 fx | 1 |
Prior unplanned excision with longitudinal incision | 4 |
Wound closure | |
Primary closure | 13 |
Regional/pedicled flap | 2† |
Free flap | 1 |
Skin graft | 1† |
Incisional wound vacuum use with surgery | 13 |
Pathologic margin status | |
R0 | 10 |
R1 | 6 |
R2 | 0 |
Abbreviations: fx = number of fractions; IMRT = intensity modulated radiation therapy; R0 = gross total resection; R1 = microscopically positive margins; R2 = macroscopically positive margins; volumetric arc therapy; VMAT = volumetric arc therapy.
Grade not available for 5 patients.
One patient underwent closure with a regional pedicle flap and a skin graft.