Table 1.
Patient and radiation therapy characteristics
| Characteristic | Mean ± SD | No. of Patient |
|---|---|---|
| Age at RT | 62.2 ± 5.6 y | |
| Primary site | ||
| Cervical: lower thoracic | 1 | |
| Middle thoracic | 11 | |
| Lower thoracic | 7 | |
| Stage (UICC 7th ed) | ||
| IA | 14 | |
| IB | 3 | |
| IIA | 1 | |
| IV | 1 | |
| Pathologic diagnosis | ||
| Squamous cell carcinoma | 19 | |
| Treatment before chemoradiotherapy | ||
| None | 15 | |
| Surgery | 1 | |
| Endoscopic submucosal dissection | 3 | |
| ECOG performance status | ||
| 0 | 15 | |
| 1 | 4 | |
| Hypertension | ||
| Yes | 4 | |
| No | 15 | |
| Hyperlipidemia | ||
| Yes | 6 | |
| No | 13 | |
| Habit of smoking | ||
| Yes | 12 | |
| No | 7 | |
| Body mass index | 21.0 ± 3.0 kg/m2 | |
| eGFR | 77.6 ± 11.9 mL/min/1.73m2 | |
| Coronary artery calcification | ||
| Yes | 11 | |
| No | 8 | |
| LV Dmean | 17.0 ± 6.1 Gy | |
| LV V10 Gy | 41.0% ± 15.1% | |
| LV V20 Gy | 34.6% ± 14.3% | |
| LV V30 Gy | 29.9% ± 13.7% | |
| LV V40 Gy | 17.8% ± 13.9% | |
| LV V50 Gy | 4.0% ± 5.9% | |
| LV V60 Gy | 1.2% ± 2.8% |
Abbreviations: ECOG = Eastern Cooperative Oncology Group; eGFR = estimated glomerular filtration rate; LV10Gy = percentage of the volume receiving 10 Gy in the left ventricle; LV Dmean = mean dose in the left ventricle; RT = radiation therapy; SD = standard deviation; UICC = Union for International Cancer Control.