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. 2020 Nov 9;15(1):1128–1136. doi: 10.1515/med-2020-0154

Table 3.

Univariate regression analyses of factors associated long-term outcome (all-cause mortality and cardiac mortality) in ACS patients, stable CAD patients and discharged patients

Facters ACS patients Stable CAD patients Discharged patients
All-cause death CV death All-cause death CV death All-cause death CV death
HR P-value HR P-value HR P-value HR P-value HR P-value HR P-value
Age 1.070 <0.001 1.052 <0.001 1.059 <0.001 1.047 0.036 1.078 0.001 1.062 <0.001
Male 0.756 0.079 0.685 0.064 1.361 0.425 0.363 0.170 0.930 0.675 1.052 0.846
Diabetes 1.797 <0.001 1.988 <0.001 1.378 0.309 1.183 0.721 1.602 0.002 1.535 0.053
Previous PCI 0.491 0.049 0.211 0.029 0.271 0.004 0.486 0.243 0.521 0.023 0.338 0.033
Previous aspirin 0.658 0.009 0.530 0.005 0.747 0.309 0.633 0.278 0.695 0.018 0.540 0.010
Previous statin 0.449 <0.001 0.381 0.002 0.892 0.708 0.810 0.638 0.781 0.165 0.494 0.018
Beta-blocker 0.622 0.010 0.504 0.001 0.422 0.019 0.183 0.021 0.625 0.009 0.467 0.009
BMIa 0.935 0.006 0.944 0.069 0.860 0.003 0.772 0.001 0.913 0.343 0.892 0.002
Grace score 1.026 <0.001 1.021 <0.001
DBP 0.984 0.005 0.987 0.073 1.015 0.212 1.007 0.697 0.993 0.254 0.998 0.782
Heart rate 1.028 <0.001 1.030 <0.001 1.033 <0.001 1.034 0.004 1.023 <0.001 1.027 <0.001
Creatinine clearanceb 0.971 <0.001 0.974 <0.001 0.970 <0.001 0.960 <0.001 0.973 <0.001 0.976 <0.001
Albumin 0.910 <0.001 0.927 <0.001 0.900 0.001 0.909 0.035 0.901 <0.001 0.923 <0.001
LDL-cholesterol 1.029 0.698 1.176 0.067 1.355 0.020 1.424 0.047 1.075 0.326 1.203 0.064
Triglyceride 0.794 0.006 0.840 0.092 1.008 0.026 0.501 0.069 1.008 0.061 0.774 0.050
HDL-cholesterol 1.303 0.060 0.942 0.828 2.489 0.038 2.283 0.199 1.506 0.001 1.226 0.426
Serum sodium 0.945 <0.001 0.939 <0.001 0.941 0.069 0.965 0.539 0.941 <0.001 0.938 0.001
Serum chloride 0.980 0.001 0.981 0.023 0.988 0.542 0.993 0.814 0.983 0.020 0.993 0.667
Left main disease 2.020 <0.001 2.510 <0.001 0.913 0.879 0.622 0.642 1.749 0.006 2.402 0.001
Triple vessel disease 2.132 <0.001 2.147 <0.001 2.799 0.002 3.638 0.004 2.180 <0.001 2.290 <0.001
PCI 0.612 0.001 0.558 0.003 0.644 0.128 0.582 0.199 0.575 <0.001 0.455 <0.001
Aspirin 0.426 0.002 0.743 0.515 0.279 <0.001 0.265 0.005 0.294 <0.001 0.331 <0.001
Clopidogrel 0.795 0.478 0.942 0.897 0.437 0.005 0.490 0.100 0.531 0.002 0.528 0.033
Statin 0.894 0.676 1.567 0.325 0.383 0.005 0.786 0.697 0.540 0.003 0.847 0.654
ACEI or ARBs 0.792 0.092 0.771 0.155 0.741 0.290 0.819 0.626 0.859 0.284 0.884 0.555
Beta-blocker 0.749 0.043 0.808 0.262 0.625 0.100 0.637 0.276 0.616 <0.001 0.615# 0.021

#Relative risk at t = 0.

ACEI: angiotensin-converting enzyme inhibitors, ARBs: angiotensin-receptor blockers, DBP: diastolic blood pressure, HR: hazard ratio, PCI: percutaneous coronary intervention, SBP: systolic blood pressure.

aBody mass index is the weight in kilograms divided by the square of the height in meters.

bCreatinine clearance was calculated using the Cockcroft-Gault equation (mL/min).