Table 3.
Facters | ACS patients | Stable CAD patients | Discharged patients | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
All-cause death | CV death | All-cause death | CV death | All-cause death | CV death | |||||||
HR | P-value | HR | P-value | HR | P-value | HR | P-value | HR | P-value | HR | P-value | |
Age | 1.070 | <0.001 | 1.052 | <0.001 | 1.059 | <0.001 | 1.047 | 0.036 | 1.078 | 0.001 | 1.062 | <0.001 |
Male | 0.756 | 0.079 | 0.685 | 0.064 | 1.361 | 0.425 | 0.363 | 0.170 | 0.930 | 0.675 | 1.052 | 0.846 |
Diabetes | 1.797 | <0.001 | 1.988 | <0.001 | 1.378 | 0.309 | 1.183 | 0.721 | 1.602 | 0.002 | 1.535 | 0.053 |
Previous PCI | 0.491 | 0.049 | 0.211 | 0.029 | 0.271 | 0.004 | 0.486 | 0.243 | 0.521 | 0.023 | 0.338 | 0.033 |
Previous aspirin | 0.658 | 0.009 | 0.530 | 0.005 | 0.747 | 0.309 | 0.633 | 0.278 | 0.695 | 0.018 | 0.540 | 0.010 |
Previous statin | 0.449 | <0.001 | 0.381 | 0.002 | 0.892 | 0.708 | 0.810 | 0.638 | 0.781 | 0.165 | 0.494 | 0.018 |
Beta-blocker | 0.622 | 0.010 | 0.504 | 0.001 | 0.422 | 0.019 | 0.183 | 0.021 | 0.625 | 0.009 | 0.467 | 0.009 |
BMIa | 0.935 | 0.006 | 0.944 | 0.069 | 0.860 | 0.003 | 0.772 | 0.001 | 0.913 | 0.343 | 0.892 | 0.002 |
Grace score | 1.026 | <0.001 | 1.021 | <0.001 | — | — | — | — | — | — | — | — |
DBP | 0.984 | 0.005 | 0.987 | 0.073 | 1.015 | 0.212 | 1.007 | 0.697 | 0.993 | 0.254 | 0.998 | 0.782 |
Heart rate | 1.028 | <0.001 | 1.030 | <0.001 | 1.033 | <0.001 | 1.034 | 0.004 | 1.023 | <0.001 | 1.027 | <0.001 |
Creatinine clearanceb | 0.971 | <0.001 | 0.974 | <0.001 | 0.970 | <0.001 | 0.960 | <0.001 | 0.973 | <0.001 | 0.976 | <0.001 |
Albumin | 0.910 | <0.001 | 0.927 | <0.001 | 0.900 | 0.001 | 0.909 | 0.035 | 0.901 | <0.001 | 0.923 | <0.001 |
LDL-cholesterol | 1.029 | 0.698 | 1.176 | 0.067 | 1.355 | 0.020 | 1.424 | 0.047 | 1.075 | 0.326 | 1.203 | 0.064 |
Triglyceride | 0.794 | 0.006 | 0.840 | 0.092 | 1.008 | 0.026 | 0.501 | 0.069 | 1.008 | 0.061 | 0.774 | 0.050 |
HDL-cholesterol | 1.303 | 0.060 | 0.942 | 0.828 | 2.489 | 0.038 | 2.283 | 0.199 | 1.506 | 0.001 | 1.226 | 0.426 |
Serum sodium | 0.945 | <0.001 | 0.939 | <0.001 | 0.941 | 0.069 | 0.965 | 0.539 | 0.941 | <0.001 | 0.938 | 0.001 |
Serum chloride | 0.980 | 0.001 | 0.981 | 0.023 | 0.988 | 0.542 | 0.993 | 0.814 | 0.983 | 0.020 | 0.993 | 0.667 |
Left main disease | 2.020 | <0.001 | 2.510 | <0.001 | 0.913 | 0.879 | 0.622 | 0.642 | 1.749 | 0.006 | 2.402 | 0.001 |
Triple vessel disease | 2.132 | <0.001 | 2.147 | <0.001 | 2.799 | 0.002 | 3.638 | 0.004 | 2.180 | <0.001 | 2.290 | <0.001 |
PCI | 0.612 | 0.001 | 0.558 | 0.003 | 0.644 | 0.128 | 0.582 | 0.199 | 0.575 | <0.001 | 0.455 | <0.001 |
Aspirin | 0.426 | 0.002 | 0.743 | 0.515 | 0.279 | <0.001 | 0.265 | 0.005 | 0.294 | <0.001 | 0.331 | <0.001 |
Clopidogrel | 0.795 | 0.478 | 0.942 | 0.897 | 0.437 | 0.005 | 0.490 | 0.100 | 0.531 | 0.002 | 0.528 | 0.033 |
Statin | 0.894 | 0.676 | 1.567 | 0.325 | 0.383 | 0.005 | 0.786 | 0.697 | 0.540 | 0.003 | 0.847 | 0.654 |
ACEI or ARBs | 0.792 | 0.092 | 0.771 | 0.155 | 0.741 | 0.290 | 0.819 | 0.626 | 0.859 | 0.284 | 0.884 | 0.555 |
Beta-blocker | 0.749 | 0.043 | 0.808 | 0.262 | 0.625 | 0.100 | 0.637 | 0.276 | 0.616 | <0.001 | 0.615# | 0.021 |
#Relative risk at t = 0.
ACEI: angiotensin-converting enzyme inhibitors, ARBs: angiotensin-receptor blockers, DBP: diastolic blood pressure, HR: hazard ratio, PCI: percutaneous coronary intervention, SBP: systolic blood pressure.
aBody mass index is the weight in kilograms divided by the square of the height in meters.
bCreatinine clearance was calculated using the Cockcroft-Gault equation (mL/min).