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. 2020 Sep 21;11(1):341–355. doi: 10.1515/tnsci-2020-0130

Figure 5.

Figure 5

The effect of feeding schedule and isoflurane anaesthesia on temperature rhythm during 7 days (D1, D2, D3, D4, D5, D6, D7). (a–d) Representative double-plotted actograms show the temperature patterns after feeding schedule and isoflurane anaesthesia in a 12 h:12 h light:dark cycle. The black sections in the actograms represent higher temperature than the average value in 48 h, while the white ones represent lower temperature, the abscissa 8.00 means ZT0; 20.00 means ZT12. Pentagram represents anaesthesia administration from ZT14 to ZT19. (e) Phase shift of acrophase. (f) Amplitude. (g) MESOR. a P < 0.05 vs Mean values in 7-day pre-administration period; b P < 0.05 vs Control + Anes group; c P < 0.05 vs Night-Feeding group; d P < 0.05 vs Night-Feeding + Anes group; e P < 0.05 vs Day-Feeding group, n = 8.