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. 2020 Nov 9;15(1):1096–1122. doi: 10.1515/med-2020-0160

Table 3.

PDNVs as drug carrier

Source of the nanovectors/nanocarriers Target Drug substances Ref.
Grapefruit Colon cancer Doxorubicin (Dox), curcumin [111]
Tumor cells (4T1, GL26, A549, CT26, or SW620) JSI-124 (anti-Stat3 inhibitor), paclitaxel (PTX), luciferase gene siRNA [32]
GL26 brain tumor cells miR17 [114]
Intestinal macrophages Methotrexate (MTX) [53]
Liver Kupffer cells miR-18a [112]
Broccoli Colon tissue Sulforaphane [64]
Apple Human epithelial colorectal adenocarcinoma (Caco-2) cells miRNAs [67]
Citrus limon Chronic myeloid leukemia (CML) Proteins [55]
Ginger Colon cancer cell lines Doxorubicin (Dox) [40]
Colon-26 cells and HT-29 cells
RAW 264.7 macrophages and Colon-26 cells siRNA-CD98 [113]
Intestinal epithelial cells (IEC) miRNA, 6-gingerol, and 6-shogaol [44]