Table 4. Chi-square test for comparisons of resistance rates to antimicrobial agents among various phylogenetic groups of uropathogenic Escherichia coli isolates.
| Antimicrobial resistance rates | Phylogenetic group | Chi- square | P-value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B2 | C | E | A | F | D | B1 | Unassignable | Clade I and I or II | Total | |||
| n = 122(%) | n = 26(%) | n = 25(%) | n = 10(%) | n = 9(%) | n = 6(%) | n = 5(%) | n = 3(%) | n = 2(%) | n = 208(%) | |||
| Penicillins | ||||||||||||
| AMP | 101 (82.8) | 25 (96.2) | 21 (84) | 8 (80) | 6 (66.7) | 6 (100) | 4 (80) | 3 (100) | 1 (50) | 175 (84.1) | 16.707 | 0.054 |
| β-lactam/ β-lactamase inhibitor combinations | ||||||||||||
| AMC | 39 (32) | 17 (65.4) | 9 (36) | 3 (30) | 4 (44.4) | 1 (16.7) | 3 (60) | 0 | 0 | 76 (36.5) | 16.906 | 0.050 |
| TZP | 2 (1.6) | 7 (26.9) | 1 (4) | 0 | 1 (11.1) | 0 | 0 | 0 | 0 | 11 (5.3) | 29.961 | 0.000 |
| SCF | 5 (4.1) | 7 (26.9) | 1 (4) | 0 | 0 | 0 | 0 | 0 | 0 | 13 (6.3) | 22.477 | 0.007 |
| Cephalosporins | ||||||||||||
| KZ | 54 (44.3) | 18 (69.2) | 11 (44) | 1 (10) | 5 (55.6) | 2 (33.3) | 1 (20) | 1 (33.3) | 0 | 93 (44.7) | 15.248 | 0.084 |
| CTX | 53 (43.4) | 18 (69.2) | 11 (44) | 1 (10) | 5 (55.6) | 1 (16.7) | 1 (20) | 1 (33.3) | 0 | 91 (43.8) | 16.977 | 0.049 |
| CRO | 53 (43.4) | 18 (69.2) | 11 (44) | 1 (10) | 5 (55.6) | 1 (16.7) | 1 (20) | 1 (33.3) | 0 | 91 (43.8) | 16.977 | 0.049 |
| CAZ | 52 (42.6) | 18 (69.2) | 11 (44) | 1 (10) | 5 (55.6) | 1 (16.7) | 2 (40) | 1 (33.3) | 0 | 91 (43.8) | 16.977 | 0.049 |
| Carbapenems | ||||||||||||
| IPM | 0 | 3 (11.5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 (1.4) | 21.307 | 0.011 |
| MEM | 0 | 3 (11.5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 (1.4) | 21.307 | 0.011 |
| ERT | 0 | 3 (11.5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 (1.4) | 21.307 | 0.011 |
| Aminoglycosides | ||||||||||||
| CN | 43 (33.6) | 12 (46.2) | 9 (36) | 1(10) | 4 (44.4) | 1 (16.7) | 1 (20) | 0 | 0 | 70 (33.7) | 10.759 | 0.293 |
| AK | 0 | 0 | 0 | 0 | 1 (11.1) | 0 | 0 | 0 | 0 | 1 (0.5) | 25.121 | 0.003 |
| NET | 0 | 0 | 0 | 0 | 1 (11.1) | 0 | 0 | 0 | 0 | 1 (0.5) | 25.121 | 0.003 |
| Fluoroquinolones | ||||||||||||
| CIP | 87 (71.3) | 25 (96.2) | 10 (40) | 4 (40) | 5 (55.6) | 1 (16.7) | 2 (40) | 2 (66.7) | 0 | 136 (65.4) | 36.148 | 0.000 |
| NOR | 88 (72.1) | 25 (96.2) | 10 (40) | 4 (40) | 5 (55.6) | 1 (16.7) | 1 (20) | 2 (66.7) | 0 | 136 (65.4) | 36.148 | 0.000 |
| LEV | 86 (70.5) | 25 (96.2) | 10 (40) | 4 (40) | 5 (55.6) | 1 (16.7) | 2 (40) | 2 (66.7) | 0 | 135 (64.9) | 35.411 | 0.000 |
| Folate pathway inhibitors | ||||||||||||
| SXT | 61 (50) | 20 (76.9) | 16 (64) | 5 (50) | 5 (55.6) | 4 (66.7) | 0 | 1 (33.3) | 0 | 113 (54.3) | 10.853 | 0.286 |
| Fosfomycins | ||||||||||||
| FOS | 0 | 0 | 0 | 1 (10) | 0 | 0 | 0 | 0 | 0 | 1 (0.5) | 19.896 | 0.019 |
Notes.
- Amp
- ampicillin
- AMC
- amoxicillin-clavulanic acid
- TZP
- piperacillin-tazobactam
- SCF
- cefoperazone-sulbactam
- KZ
- cefazolin
- CTX
- cefotaxime
- CRO
- ceftriaxone
- CAZ
- ceftazidime
- CN
- gentamicin
- CIP
- ciprofloxacin
- NOR
- norfloxacin
- LEV
- levofloxacin
- SXT
- trimethoprim-sulfamethoxazole
- IPM
- Imipenem
- MEM
- meropenem
- ERT
- ertapenem
- CN
- gentamicin
- AK
- amikacin
- NET
- netilmicin
- FOS
- fosfomycin