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. 2020 Dec 2;8:e10386. doi: 10.7717/peerj.10386

Table 3. KEGG analysis of DEGs in CESC.

Pathway ID Name Count p-Value Genes
04110 Cell cycle 13 7.76E−6 PCNA, CDKN2A, BUB1B, CDC7, TTK, SMC1B, CDC20, CCNB1, PTTG1, CDK1, MCM4, MCM5, MCM2
05200 Pathways in cancer 29 2.77E−5 LAMA2, CKS1B, FGF7, EDNRA, EDNRB, RUNX1T1, PDGFRB, PDGFRA, JUP, CDKN2A, MMP1, ITGA2, PTCH1, FN1, IGF2, MITF, FOS, IGF1, WNT16, GNG11, ESR1, AR, CXCL12, GSTA4, CKS2, BIRC5, FGFR2, GSTM5, FGF10
04512 ECM-receptor interaction 9 1.36E−4 TNXB, VWF, LAMA2, ITGA2, ITGA8, SPP1, FN1, HMMR, ITGA9
05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8 2.93E−4 GJA1, LAMA2, JUP, ITGA2, ITGA8, DSG2, DSC2, ITGA9
05218 Melanoma 8 2.93E−4 PDGFRB, PDGFRA, FGF7, CDKN2A, PDGFD, MITF, IGF1, FGF10
04151 PI3K-Akt signaling pathway 20 3.18E−4 PDGFRB, PDGFRA, TNXB, VWF, LAMA2, ITGA2, IGF2, FN1, IGF1, GNG11, AREG, EREG, GYS2, FGF7, PDGFD, SPP1, ITGA8, FGFR2, FGF10, ITGA9
04510 Focal adhesion 13 9.45E−4 PDGFRB, PDGFRA, TNXB, VWF, LAMA2, ITGA2, FN1, IGF1, MYLK, PDGFD, SPP1, ITGA8, ITGA9
04270 Vascular smooth muscle contraction 10 0.001189 ACTA2, GUCY1A2, PPP1R14A, EDNRA, EDN3, MYH11, MRVI1, AVPR1A, ACTG2, MYLK
03030 DNA replication 5 0.001491 PCNA, RFC4, MCM4, MCM5, MCM2
04114 Oocyte meiosis 9 0.002920 CDC20, AR, CCNB1, PTTG1, CDK1, PGR, IGF1, SMC1B,AURKA