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Intraocular pressure (a), pattern ERG (b), and OKR (c, d) in rats. IOP of conscious animals was measured at every week using Tonolab. Pattern-ERG, spatial acuity, and contrast threshold were measured at day 0 (prior) and 42 (post), prior and post injury. Brown Norway rats were treated with 1 mg/kg SNC-121 (i.p.) 1 hour after hypertonic saline injections, and subsequently once daily for 7 days. Data are expressed as mean ± SE. *, # P < 0.05; ***P < 0.001; ****P < 0.0001; n = 7–8.
