Table 4.

Correlation Analysis Between Hub Genes and Clinical Characteristics

Group	Hub Gene	Age	BUT	S1T	FL	DM Duration
Adult
	LYZ	−0.114	0.699***	0.709***	−0.260	−0.607**
	AZGP1	−0.066	0.679***	0.696***	−0.265	−0.590**
	DNAJC3	−0.090	0.684***	0.692***	−0.274	−0.586**
Child
	PGK1	0.183	−0.062	−0.266	−0.069	0.309

The correlation analysis between adult hub genes and age, BUT, FL adopts Pearson correlation coefficient, and the correlation analysis with S1T and DM duration adopts the Spearman correlation coefficient.

The correlation analysis between child hub gene and age, S1T adopts Pearson correlation coefficient, the correlation analysis with BUT, FL, DM duration adopts spearman correlation coefficient. **, *** indicate that the hypothesis test is statistically significant at the 1% and 0.1% confidence levels, respectively.

S1t, Schirmer 1 test; FL, fluorescein staining.