Figure 2.
Effect of BMY-7378 pretreatment on phenylephrine induced secretory response of isolated lacrimal gland ducts. Isolated ducts were stimulated with phenylephrine (10 µM) either in the presence or in the absence of α1D-receptor antagonist BMY-7378 (100 µM). Secretory response of ducts was measured with video-microscopy. Changes in relative luminal volume (LVr) are shown. Data were obtained at least from six ducts isolated from three different animals in each series and are presented as means ± SEM.