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. 2020 Nov 3;143(11):3225–3233. doi: 10.1093/brain/awaa264

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© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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3D MRSI for an acute ischaemic stroke patient brain at a nominal spatial resolution of 2.0 × 3.0 × 3.0 mm³ in an 8-min scan. (A) 3D lactate map in triplanar views overlaid on T₁-weighted images. The representative spectra were acquired from the infarct core (red), infarct growth (blue) and oligemia (light green) regions, respectively. (B) 3D NAA map in triplanar views overlaid on T₁-weighted images. The representative spectra were acquired from the infarct core (red), infarct growth (blue) and oligemia (light green) regions, respectively. (C) Timeline of the experimental study.