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Unmet needs in NPSLE
| Diagnostic biomarkers for determining the attribution of NP events to SLE |
| Potential candidates: CSF and serum proteins, neuroimaging |
| Novel therapies for NPSLE |
| Potential targets: BBB, pro-inflammatory cytokines, microglia |
| Advancing clinical trials for NPSLE. |
| Potential options: drugs for non-emergent NP events (e.g. mood disorders), validate outcome measures (e.g. self-report instruments, neuroimaging for brain structure and function) |
