Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 26;12(12):2403–2416. doi: 10.1093/gbe/evaa226

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Fig. 1 — Phylogenetic tree of kinetoplastid ACs. Maximum-likelihood phylogenetic tree of kinetoplastid ACs based on a trimmed alignment of 631 sequences. Scale bar on top left represents 0.5 substitutions per site. The support values are in the following format: SH-aLRT support (%)/bootstrap support (%)/posterior probability. Only bootstrap support values ≥50% and posterior probabilities ≥0.50 are shown; nodes displaying maximal supports are marked with gray circles. “Trypanosoma clade 1” and “Trypanosoma clade 2” contain the genes of salivarian clades (T. congolense, T. brucei brucei, T. brucei gambiense, T. evansi, and T. equiperdum) upregulated in bloodstream and procyclic forms, respectively (see supplementary file S1, Supplementary Material online for details). OACs, oxygen-sensing adenylate cyclases from Leishmaniinae and other species (complete tree in fig 4). “Leishmaniinae clade 1” and “Leishmaniinae clade 2” contain homologs of leishmanial RAC-A and RAC-B sequences. The number of sequences within each collapsed clade is shown in gray color in the brackets.