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Resting-state functional connectivity of the right anterior insular cortex. Brain regions showing a significant increase in the functional connectivity of the right anterior insular cortex in patients with knee osteoarthritis relative to controls (p < 0.001 uncorrected, peak-level and p < 0.05 cluster-level, after FWE correction).
Abbreviations: FWE, family-wise error; Rt, right; Bil, bilateral; OFC, orbitofrontal cortex; SCA, subcallosal area; FP, frontal pole.
