Table 3.

Correlation Between the Anterior Insular Cortex-Right Orbitofrontal Cortex Functional Connectivity and Clinical Measurements

Lt.aIC-Rt.OFC	WOMAC total	WOMAC pain	WOMAC stiffness	WOMAC physical
cc	0.29	0.49*	0.15	0.23
p	0.22	0.03	0.52	0.34
	VAS	Pain-DETECT	PCS
cc	0.26	−0.02	0.05
p	0.28	0.92	0.84
Rt.aIC-Rt.OFC	WOMAC total	WOMAC pain	WOMAC stiffness	WOMAC physical
cc	0.48*	0.46*	0.24	0.37
p	0.04	0.049	0.31	0.12
	VAS	Pain-DETECT	PCS
cc	0.26	−0.01	0.02
p	0.28	0.97	0.94

Note: *p < 0.05 denotes significant correlation.

Abbreviations: Lt, left; Rt, right; aIC, anterior insular cortex; cc, Spearman’s rank correlation coefficients; OFC, orbitofrontal cortex; PCS, Pain Catastrophizing Scale; VAS, visual analog scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.