Table 5.
Treatment characteristics and follow-up of the six patients who were treated for RCAD
| Case | Total dose
(Gy) |
Dose/fraction
(Gy) |
Field | Chemotherapy | Location of stenosis | Duration of RT
administration (months) |
Vascular
Symptom |
Treatment | Current
status (months) |
|
| 1 | 60 | 2 | WN | FN | ICA | In-field | 44.9 | TIA | Stenting | NED (120) |
| 2 | 63 | 2.25 | Box | None | ICA | Out-of-field | 49.7 | None | Stenting | NED (103) |
| 3 | 63 | 2.25 | Box | None | ICA | Out-of-field | 78.3 | None | Stenting | NED (78.3) |
| 4 | 70 | 2 | WN | CDDP | ICA | In-field | 62.7 | Stroke | Medication | NED (66.9) |
| 5 | 63 | 2.25 | Box | None | CCA | In-field | 53.6 | Stroke | Medication | NED (55.7) |
| 6 | 70 | 2 | Box | None | ICA | Out-of-field | 0.3 | Stroke | Medication | NED (35) |
RCAD: Radiation-induced carotid artery disease
BMI: body mass index
WN: whole neck field including subclinical lymph node
Box; parallel-opposed fields with individualized wedge-filtered technique, 5 × 5 or 6 × 6 cm; FN, combined with the use of nedaplatin and 5-fluorouracil; CDDP, cisplatin
ICA: internal carotid artery
CCA: common carotid artery
RT: radiotherapy
TIA: transient ischemic attack
NED: no evidence of primary disease