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Tetrandrine (Tet) inhibits the expression of proinflammatory cytokines. (a) Immunohistochemical staining of tumor necrosis factor (TNF)-α. (b) Immunohistochemical staining of interleukin (IL)-1β. (c) Immunohistochemical staining of IL-6. The mean density for TNF-α, IL-1β, and IL-6 were quantified (∗p < 0.05, ∗∗p < 0.01 compared with the vehicle group; n = 5 per group). Black arrows indicate positive expression, respectively.
