TABLE 1.
Characteristics | Number (%), mean ± SD |
---|---|
Age at transplant (mean ± SD) | 49.76 ± 14.42 |
Living donor | 534 (62.6) |
Simultaneous pancreas-kidney | 35 (4.1) |
Weight (kg) at transplant (mean ± SD) | 81.75 ± 20.56 |
Male recipient | 521 (61.1) |
Male donor | 419 (49.1) |
Ancestry | |
European | 678 (79.5) |
African | 175 (20.5) |
Cause of kidney diseasea | |
Diabetes | 178 (20.9) |
Glomerular disease | 243 (28.5) |
Other | 156 (18.3) |
Hypertension | 100 (11.7) |
Polycystic kidney disease | 126 (14.8) |
Unknown | 50 (5.9) |
Cardiovascular disease prior to transplanta | |
Myocardial infarction | 45 (5.3) |
Stroke | 39 (4.6) |
Hypertension | 755 (88.5) |
Congestive heart failure | 47 (5.5) |
CAD requiring drug treatment | 99 (11.6) |
CAD requiring invasive or surgical procedures | 107 (12.5) |
Hyperlipidaemia requiring drug treatment at transplant | 429 (50.3) |
Diabetes at time of transplant | 250 (29.3) |
Induction immunosuppression | |
Monoclonal antibody | 339 (39.7) |
Polyclonal antibody | 496 (58.1) |
Combination | 18 (2.1) |
Calcineurin inhibitor at baseline | |
Tacrolimus | 776 (91.0) |
Cyclosporine | 62 (7.3) |
None | 15 (1.8) |
Abbreviation: CAD, coronary artery disease.
The number of cardiovascular diseases exceeds 100% since some individuals had multiple conditions.