Figure 1. Morphological impacts of Coil29Caps and Coil29Kinks.

A) Circular Dichroism of individual peptides in PBS, diluted to 0.1 mM in water immediately prior to scanning. Reported spectra are averaged from 3 scans and error bars indicate standard deviation. B) AFM images of nanofibers formed from Coil29 alone (left), incorporating a 1:10 ratio of Coil29Caps:Coil29 (center) or incorporating a 1:10 ratio of Coil29Kink:Coil29 (right). C) Length distributions of nanofibers formed with capping and kinking peptides, calculated as percent of total peptides in fibers of a given length (n=3 images per condition). D) Box and whisker plots showing 25^th percentile, 50^th, and 75^th percentile with error bars at 10 and 90 percentile range. Nanofiber lengths were compared using the Kruskal-Wallis test with Dunn’s multiple comparisons (*p<0.05, ****p<0.0001).