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. 2020 Nov 23;8:580131. doi: 10.3389/fcell.2020.580131

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Copyright © 2020 Zhao, Zhang, Lu, Huang, Wang, Shao and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo Matrigel plug angiogenesis assay. (A) Full view, H&E (Gross), CD31 (Gross, 200X) of the Matrigel plug one week after subcutaneous transplantation in nude mice. Gross (H&E, CD31): Scale bar = 2 mm. 200X (CD31): Scale bar = 200 μm. (B) Quantitative analysis on the number and area of CD31 positive vessels was measured. Image analysis was performed on three random fields per sample (n = 5 samples, *denotes P < 0.05 vs. NPC-ASC^CM; ^#denotes P < 0.05 vs. HPC-ASC^CM + anti-VEGF-A/SDF-1a).