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. 2020 Nov 23;11:574535. doi: 10.3389/fphys.2020.574535

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Copyright © 2020 Ding, Wang, Yin, Wang, Gong, Liao and Liang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–D) Bar graphs of blood perfusion change, cerebral infarction area, vascular injury area, and endothelial factors. Protein expression in the model group and sham-operated group. (E) Bar graphs of gene expression in the model group and control group without the intervention of shear stress and drugs. All data are expressed as the mean ± SD. Comparisons between the sham group and model group were analyzed using the independent-sample t-test. A value of p < 0.05 was considered statistically significant.