Table 1.
Swimming (min) | CPSM (mg kg−1) | Blood perfusion changes (PU) | Infarct area proportion (%) | Vascular injury area proportion (%) | |||
---|---|---|---|---|---|---|---|
Sham-operated | −24.65 ± 5.87 | 0 | 0 | ||||
0 | 0 | −137.72 ± 34.39 | 11.90 ± 3.05 | 27.65 ± 8.92 | |||
0 | 237 | −146.10 ± 30.38 | 10.90 ± 1.86 | 23.35 ± 6.25 | |||
0 | 474 | −119.81 ± 30.40 | 10.13 ± 3.06 | 22.05 ± 4.78 | |||
20 | 0 | −119.86 ± 29.95 | 10.62 ± 3.18 | 20.92 ± 6.59 | |||
20 | 237 | −116.98 ± 29.27 | 8.32 ± 2.80 | 15.21 ± 3.67 | |||
20 | 474 | −112.65 ± 31.49 | 10.28 ± 2.85 | 21.58 ± 6.32 | |||
40 | 0 | −118.70 ± 21.68 | 4.76 ± 1.04 | 20.54 ± 6.49 | |||
40 | 237 | −78.47 ± 23.27 | 7.45 ± 1.43 | 11.54 ± 1.33 | |||
40 | 474 | −127.28 ± 44.34 | 4.89 ± 1.47 | 18.15 ± 6.23 | |||
Two-way ANOVA | F | p | F | p | F | p | |
Swimming | 4.86 | 0.01 | 21.73 | <0.001 | 7.87 | <0.001 | |
CPSM | 0.31 | 0.73 | 0.39 | 0.68 | 6.70 | <0.001 | |
CPSM × swimming | 3.36 | 0.02 | 0.55 | 0.70 | 1.67 | 0.17 |
All data are expressed as the mean ± SD. The GLM procedure was applied for a two-way ANOVA to test for synergy. Comparisons between each pair of factor levels were analyzed using a Bonferroni post hoc test. A value of p < 0.05 was considered statistically significant.